Effect of Garlic Tablet Some Indicators Related to Atherosclerosis

NCT ID: NCT01948453

Last Updated: 2015-05-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

56 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-08-31

Study Completion Date

2014-09-30

Brief Summary

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The purpose of this study is to determine whether garlic in adjunct to conventional medical treatment is effective in improving carotid intima media thickness (CIMT), Flow mediated dilation (FMD) and plasma lipid profile or c-reactive protein of coronary artery disease (CAD) patients.

Detailed Description

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Conditions

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Coronary Artery Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Garlic

daily consumption of two odor controlled garlic tablets

Group Type ACTIVE_COMPARATOR

Garlic

Intervention Type DIETARY_SUPPLEMENT

Garlic tablet in adjunct to medical treatment

Placebo

daily consumption of placebo

Group Type PLACEBO_COMPARATOR

No interventions assigned to this group

Interventions

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Garlic

Garlic tablet in adjunct to medical treatment

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* angiography confirmed coronary artery disease
* lack of consistent use of the garlic in the last month

Exclusion Criteria

Change in type of medication during study
Minimum Eligible Age

25 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Shahid Beheshti University

OTHER

Sponsor Role lead

Responsible Party

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Javad Nasrollahzadeh

Dr.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Javad Nasrollahzadeh, Ph.D.

Role: STUDY_CHAIR

Department of Clinical Nutrition and Diet Therapy, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences

Ali Z Mehr, M.D.

Role: STUDY_DIRECTOR

Department of Cardiology, Rajaei Cardiovascular, Medical & Research Center

Marjan M Roshan, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Department of Clinical Nutrition and Diet Therapy, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences

Locations

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Rajaei Cardiovascular, Medical & Research Center

Tehran, , Iran

Site Status

Countries

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Iran

Other Identifiers

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513

Identifier Type: -

Identifier Source: org_study_id

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