Enhanced Cognitive Rehabilitation to Treat Comorbid TBI and PTSD

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

108 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-08-31

Study Completion Date

2017-09-30

Brief Summary

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This study will test a modification of Cognitive Processing Therapy (CPT) for Post-Traumatic Stress Disorder, (PTSD) in which CPT is augmented with compensatory cognitive rehabilitation principles from the Cognitive Symptom Management and Rehabilitation Therapy (CogSMART) intervention to create a hybrid treatment, SMART-CPT. This study investigates the efficacy of SMART-CPT in improving PTSD and post-concussive symptoms, cognition, quality of life, and treatment compliance in those with a history of mild to moderate TBI and persistent cognitive complaints.

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Detailed Description

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Conditions

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PTSD With a History of Mild to Moderate TBI

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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SMART-CPT

CPT with additional elements of cognitive rehabilitation

Group Type EXPERIMENTAL

CPT

Intervention Type BEHAVIORAL

CPT

Standard Cognitive Processing Therapy

Group Type ACTIVE_COMPARATOR

CPT

Intervention Type BEHAVIORAL

Interventions

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CPT

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

1\) OEF/OIF veteran; 2) Current diagnosis of PTSD; 3) History of mild-to-moderate TBI; 4) Subjective cognitive complaints; 5) No anticipated/pending medication changes; 6) Written informed consent to participate in the study. -