Modeling Between Plasma Concentration and Serotonin Transporter Occupancy Induced by Escitalopram in Obsessive-compulsive Disorder(OCD) Patients
NCT ID: NCT01936051
Last Updated: 2019-04-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
12 participants
OBSERVATIONAL
2012-02-29
2013-12-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
To examine the effect of G2677T/A single nucleotide polymorphism(SNP) of ABCB1 gene to the PK-PD modeling in OCD patients treated with escitalopram.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Tolerability and Efficacy of High Dose Escitalopram for the Treatment of Obsessive-Compulsive Disorder (OCD)
NCT00305500
The Role of Serotonin in Compulsive Behavior in Humans: Underlying Brain Mechanisms
NCT04336228
Escitalopram Combination Comparison Study for Adult Patients With Major Depressive Disorder
NCT00239954
Pharmacokinetic and Pharmacodynamic Effects of Escitalopram Depending on Genetic Polymorphisms of the ABCB1-gene
NCT00550485
Effect of Antidepressants on the Treatment for Korean Major Depressive Disorder Patients
NCT00926835
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
To measure serotonin transporter occupancy by escitalopram in OCD patients treated with escitalopram.
To genotype G2677T/A SNP of ABCB1 gene in OCD patients treated with escitalopram.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
OTHER
OTHER
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
OCD patients
OCD patients being treated with any dose of escitalopram
No interventions assigned to this group
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* no change of escitalopram dosage in 6 weeks
Exclusion Criteria
* History of head injury, epilepsy, other general medical disorder
20 Years
35 Years
MALE
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Seoul National University Hospital
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Jun Soo Kwon
Modeling Between Plasma Concentration and Serotonin Transporter Occupancy Induced by Escitalopram in OCD Patients
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Jun Soo Kwon, M.D, Ph.D
Role: PRINCIPAL_INVESTIGATOR
Seoul National University Hospital
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Seoul National University Hospital
Seoul, , South Korea
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
2011-0931
Identifier Type: OTHER
Identifier Source: secondary_id
H-1109-086-378
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.