Beta-CIT-SPECT and Neurophysiology in Depression

NCT ID: NCT00145132

Last Updated: 2010-06-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-06-30

Study Completion Date

2009-12-31

Brief Summary

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Aim of this project is to investigate the effects of escitalopram on monoamine transporter (SERT, DAT) availabilities as assessed by b-CIT and SPECT, and on neurophysiological parameters such as the loudness dependence of auditory evoked potentials (LDAEP) in patients with depression.

Detailed Description

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Conditions

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Depression

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Interventions

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β-CIT-SPECT, Neurophysiology

β-CIT-SPECT scans and EEG recordings, two assessments each

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Psychiatric in or outpatients with acute depressive episode
* Indication for pharmacological treatment

Exclusion Criteria

* Acute suicidality
* Neurological or severe somatic disorders
* Occupational exposition to radiation \>15 mSv per year
* Women during pregnancy or lactation
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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H. Lundbeck A/S

INDUSTRY

Sponsor Role collaborator

Ludwig-Maximilians - University of Munich

OTHER

Sponsor Role lead

Responsible Party

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University of Munich

Principal Investigators

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Oliver Pogarell, MD

Role: PRINCIPAL_INVESTIGATOR

Dept. of Psychiatry, University of Munich

Locations

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Depts. of Psychiatry and Nuclear Medicine, Ludwig-Maximilians-University of Munich

Munich, , Germany

Site Status

Countries

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Germany

Other Identifiers

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EK287/98

Identifier Type: -

Identifier Source: secondary_id

ESCIT-SPECT-Pogarell

Identifier Type: -

Identifier Source: org_study_id

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