MedDataX Logo

Evaluation of Ventilatory Strategies During Laparoscopic Surgery

NCT ID: NCT01923038

Last Updated: 2014-01-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-11-30

Study Completion Date

2013-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Atelectasis involving declive areas often occurs during general anesthesia and may persist postoperatively. This phenomenon could be amplified by pneumoperitoneum and Trendelenburg position. Hypothesis: To evaluate whether the shape of the airway pressure-time curve, Stress Index (SI), during constant flow inflation can lead ventilator setting during general anesthesia.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Very Low Tidal Volume vs Conventional Ventilatory Strategy for One-lung Ventilation in Thoracic Anesthesia

NCT01504893

Acute Respiratory Distress Syndrome
COMPLETED NA

Transpulmonary Pressure Under Stressing Conditions

NCT03746236

Ventilator-Induced Lung Injury
UNKNOWN

Prevention of Perioperative Pulmonary Complications by Lung Recruitment During Laparoscopic Surgery

NCT04728945

Perioperative Complication Hypoxia
UNKNOWN NA

Effect of Recruitment Maneuvers Plus Optimal PEEP Versus Optimal PEEP Alone in One Lung Ventilation

NCT03635281

Mechanical Ventilation Complication
COMPLETED NA

Recruitment-to-inflation Ratio to Set Positive End-expiratory Pressure for Laparoscopic/Robotic Surgery: a Multicenter Study

NCT05702554

Respiratory System Mechanics Pneumoperitoneum
UNKNOWN

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Pneumonia

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Patients ventilated with zero end expiratory pressure (ZEEP)

patients undergoing gynecologic laparoscopic surgery ventilated at zero end expiratory pressure

Group Type ACTIVE_COMPARATOR

First arm: patients ventilated with zero end expiratory pressure

Intervention Type PROCEDURE

Patients ventilated with positive end expiratory pressure

patients undergoing gynecologic laparoscopic surgery ventilated at PEEP

Group Type ACTIVE_COMPARATOR

Patients ventilated with Positive End Expiratory Pressure

Intervention Type PROCEDURE

recruitment plus PEEP

patients undergoing gynecologic laparoscopic surgery undergoing recruitment plus PEEP

Group Type ACTIVE_COMPARATOR

Patients ventilated with Positive End Expiratory Pressure plus Recruitment maneuver

Intervention Type PROCEDURE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

First arm: patients ventilated with zero end expiratory pressure

Intervention Type PROCEDURE

Patients ventilated with Positive End Expiratory Pressure

Intervention Type PROCEDURE

Patients ventilated with Positive End Expiratory Pressure plus Recruitment maneuver

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* American Society Anesthesiology (ASA) I, II;
* age \> 18 years;
* elective surgery

Exclusion Criteria

* ASA III, IV;
* Age \< 18 years;
* emergency surgery
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Maria Vittoria Hospital

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Emilpaolo Manno

Emergency Department Director

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Emilpaolo Manno, MD

Role: STUDY_DIRECTOR

Maria Vittoria Hospital

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Maria Vittoria Hospital

Turin, Turin, Italy

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Italy

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

MariaVittoria Hospital

Identifier Type: OTHER

Identifier Source: secondary_id

BCB232

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Effect of Perioperative Lung Protective Strategies on the Occurrence of Postoperative Pulmonary Complications in Patients Undergoing Lumbar Spinal Surgery in the Prone Position
NCT02373475 COMPLETED PHASE4
Individualized Selection of PEEP in Patients Affected by Expiratory Flow Limitation
NCT06215001 NOT_YET_RECRUITING NA
Comparison of Hemodynamic Effect of 2 Methods for Alveolar Recruitment Maneuver in Anesthetized Patients
NCT03215329 UNKNOWN
Optimal Interval for Periodic Alveolar Recruitment Maneuvers Achieving 90% Lung Re-expansion During Intraoperative Ventilation
NCT07239557 NOT_YET_RECRUITING NA
Individualized Perioperative Open-Lung Ventilatory Strategy During One-Lung Ventilation
NCT03182062 UNKNOWN NA
The Effect of Recruitment Maneuver With Protective Ventilation During Thoracic Surgery
NCT01630395 COMPLETED NA
The Strategy of "Pulmonary Opening by Titration of Positive End-expiratory Pressure" Means of a Pulmonary Recruitment Maneuver in Patients With Acute Respiratory Distress Syndrome: for Which Patients?
NCT04028336 TERMINATED NA
The Open Lung Approach During One Lung Ventilation in Thoracic Surgery
NCT03435523 COMPLETED NA
Individualized Perioperative Open Lung Ventilatory Strategy
NCT02158923 COMPLETED NA
Ventilator-driven Alveolar Recruitment Maneuver
NCT04258202 COMPLETED NA
The Effects of Different Types of Non-ventilated Lung Management on DO2 During OLV in the Supine Position
NCT02959515 UNKNOWN NA
Prevention of Postoperative Respiratory Complications
NCT06899295 NOT_YET_RECRUITING
Individualized Intraoperative PEEP Following Alveolar Recruitment Maneuvres and Postoperative Respiratory Complications
NCT06600386 COMPLETED PHASE2
Intra-operative Ventilatory Management & Post-operative Pulmonary Complications
NCT03551899 COMPLETED
Driving Pressure-guided PEEP Titration in Robot-assisted Laparoscopic Surgeries
NCT04327193 COMPLETED NA
Comparison of Spontaneous Ventilation Time in Air Without Desaturation After Positive Pressure Extubation Versus Aspiration Extubation When Awakening From General Anesthesia
NCT01323049 COMPLETED NA
Physiological Effects of Lung Recruitment During General Anesthesia and Low-tidal Volume Ventilation
NCT03083457 COMPLETED NA
Nondependent Lung Ventilation and Fluid Responsiveness
NCT02191410 UNKNOWN PHASE3
Ventilation Strategy Reduces Postoperative Atelectasis
NCT01911923 WITHDRAWN NA
Alveolar Recruitment Maneuver During Cesarean Section Improves Lung Compliance
NCT01826968 COMPLETED PHASE2
Non Invasive Pressure Support Ventilation (NIPPV) Versus Recruitment Maneuver (RM) and Preoxygenation
NCT00852384 COMPLETED PHASE4
Optimizing Intraoperative Mechanical Ventilation Using EIT-titrated PEEP
NCT02314845 COMPLETED NA
Effects of Mechanical Ventilation Guided by Transpulmonary Pressure on Gas Exchange During Robotic Surgery: a Pilot Study
NCT03153592 COMPLETED NA
Mechanical Ventilation During Cardiac Surgery
NCT02090205 UNKNOWN NA
Ventilation Strategies Impact on Oxygenation and Postoperative Pulmonary Complications in Lung Surgery Patients
NCT06805760 NOT_YET_RECRUITING NA