Episodic Memory Before and After Surgery in Drug-resistant Partial Epilepsies

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-10-31

Study Completion Date

2022-12-31

Brief Summary

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This study has two purposes: firstly, a better understanding of the neurobiological processes underlying episodic memory and, secondly, the development of useful clinical applications for epileptic patients, in particular the prediction of postoperative memory deficits and the development of cognitive remediation therapies.

Memory performances during a fMRI experiment will be assessed in controls and epileptic patients before and after the surgery.

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Detailed Description

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Conditions

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Epilepsy, Unspecified, Pharmacologically Resistant Memory Impairment

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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memory outcome

Group Type NO_INTERVENTION

No intervention

Intervention Type OTHER

Interventions

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No intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients with drug-resistant epilepsy
* Age of 18 years or more
* Follow-up in the epilepsy unit at Pitié-Salpêtrière Hospital
* Before or after the presurgical evaluation unit including a video-EEG monitoring, a structural brain imaging and a full neuropsychological assessment
* Covered by a social security system
* Signing of consent form

Exclusion Criteria

* Persons under guardianship, curatorship or any other administrative or judicial deprivation of rights and freedom
* Refusal to consent form
* Contraindications to MRI
* Pregnancy
* Refusal to be informed in the case of detection of an abnormality during the experiment

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes