The Effect of a Deep-fried Chocolate Bar or Porridge on Cerebral Blood Flow

NCT ID: NCT01918137

Last Updated: 2013-08-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-08-31

Study Completion Date

2013-09-30

Brief Summary

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The deep fried chocolate bar is a snack that the international community strongly associates with Scotland. It has previously been cited as being "a symbol of all that is wrong with the high-fat, high-sugar Scottish diet". Despite the snack's reputation, no medical research has been performed to examine the effects of consuming a deep fried chocolate bar on the human body.

In contrast to the deep fried chocolate bar, porridge has been shown to reduce the risk of cardiovascular disease, but its effect on cerebral blood flow has yet to be directly assessed.

This study will focus on the potential (patho)physiological cerebrovascular effects of the deep fried chocolate bar and porridge. The research question to be addressed in this study is "Does eating a deep fried chocolate bar or bowl of porridge induce changes in cerebral blood flow and cereborvascular reactivity in healthy adults?"

To assess the acute effects on eating either food on blood flow through the largest artery in the brain, the investigators will give healthy volunteers one regular-sized deep-fried chocolate bar or a bowl of porridge. Blood flow through the largest artery in the brain will be assessed using simple ultrasounds tests. The investigators aim to recruit 24 volunterrs who will visit twice, consuming a different food on each visit.

Detailed Description

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Conditions

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Effect on Cerebrovascular Reactivity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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chocolate bar

Group Type EXPERIMENTAL

chocolate bar

Intervention Type DIETARY_SUPPLEMENT

porridge

Group Type EXPERIMENTAL

Porridge

Intervention Type DIETARY_SUPPLEMENT

Interventions

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chocolate bar

Intervention Type DIETARY_SUPPLEMENT

Porridge

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* BMI between 18 and 30
* No regular medication
* Able to provide informed consent

Exclusion Criteria

* Distaste for or contraindication to deep-fried chocolate bar or porridge ingestion
* inability to perform breath-hold
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Glasgow

OTHER

Sponsor Role collaborator

NHS Greater Glasgow and Clyde

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Western Infirmary

Glasgow, , United Kingdom

Site Status

Countries

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United Kingdom

Central Contacts

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Matthew Walter, MBChB, MSc, FRCP, MD

Role: CONTACT

Email: [email protected]

Erica Packard, PhD

Role: CONTACT

Email: [email protected]

Facility Contacts

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Matthew Walters, MBChB, MSc, FRCP, MD

Role: primary

Other Identifiers

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GN13MT357

Identifier Type: -

Identifier Source: org_study_id