Low-dose Spinal Morphine for Post-Thoracotomy Pain After Video-Assisted Thoracoscopic Surgery

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

36 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-02-28

Study Completion Date

2016-01-31

Brief Summary

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One-thirds of patients underwent video-assisted thorascopic surgery still have severe pain. Therefore we want to demonstrate weather 0.15 mg spinal morphine would reduce 24 hour postoperative requirement comparing to control group.

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Detailed Description

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Conditions

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Video-assisted Thoracoscopic Surgery

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Control

The skin will be injected with local anesthetic without spinal block

Group Type SHAM_COMPARATOR

control

Intervention Type OTHER

Patient receive only local infiltration without spinal analgesia

Spinal morphine

0.15 mg spinal morphine

Group Type ACTIVE_COMPARATOR

Morphine

Intervention Type DRUG

spinal morphine 0.15 mg

Interventions

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Morphine

spinal morphine 0.15 mg

Intervention Type DRUG

control

Patient receive only local infiltration without spinal analgesia

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* ASA (American Society of Anesthesiologist) physical status I to III,
* Undergoing elective video-assisted thoracoscopic surgery at Siriraj and Thammasart Hospitals
* capable of using a patient-controlled analgesia (PCA) machine
* understanding the numeric rating scale (NRS) score for pain assessment.

Exclusion Criteria

* history of allergy to the study drugs
* bleeding disorder
* infection of the back
* refusing spinal anesthesia
* history of cerebrovascular disease
* using postoperative ventilator support were excluded

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No