Influence of Adipocytokines in Osteoarthritis

NCT ID: NCT01906281

Last Updated: 2013-11-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

105 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-07-31

Study Completion Date

2014-12-31

Brief Summary

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Adipocytokines play an important role in joint inflammation in patients with knee osteoarthritis as measured by ultrasound and high sensitivity protein-C reactive. Adipocytokines could be the link between osteoarthritis and cardiovascular risk factors more prevalent in these patients.

Detailed Description

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Conditions

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Osteoarthritis, Knee Endocrine System Diseases Cardiovascular Risk Factors

Keywords

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adipocytokines osteoarthritis cardiovascular risk

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Inflammatory knee osteoarthritis

One group of patients with inflammatory condition in physical evaluation. We will make a blood analyse and arthrocentesis when synovial fluid were found in ultrasound examination. Ultrasound of affected knee and carotid artery will be performed.

Blood analyse, arthrocentesis, ultrasound examination

Intervention Type OTHER

Non-inflammatory knee osteoarthritis

Patients with no inflammatory condition in physical examination. We will make a blood analyse and arthrocentesis when synovial fluid were found in ultrasound examination. Ultrasound of affected knee and carotid artery will be performed.

Blood analyse, arthrocentesis, ultrasound examination

Intervention Type OTHER

Interventions

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Blood analyse, arthrocentesis, ultrasound examination

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients over 50 years old with symptomatic knee osteoarthritis.

Exclusion Criteria

* Patients with secondary osteoarthritis of the knee
* Any other rheumatologic condition.
Minimum Eligible Age

50 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Parc TaulĂ­ Hospital Universitari

OTHER

Sponsor Role lead

Responsible Party

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Joan Calvet Fontova

Dr

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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jordi Gratacos, MD Ph

Role: STUDY_DIRECTOR

Hospital Parc Tauli

Locations

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Hospital Parc Tauli Sabadell

Sabadell, Barcelona, Spain

Site Status RECRUITING

Hospital Parc Tauli

Sabadell, Barcelona, Spain

Site Status RECRUITING

Countries

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Spain

Central Contacts

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Joan Calvet, Dr

Role: CONTACT

Phone: 0034 937231010

Email: [email protected]

Cristobal Orellana, Dr

Role: CONTACT

Phone: 0034 937231010

Email: [email protected]

Facility Contacts

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Joan Calvet, Dr

Role: primary

Joan Calvet, Dr

Role: primary

Cristobal Orellana, Dr

Role: backup

Other Identifiers

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Joan01

Identifier Type: -

Identifier Source: org_study_id