Efficacy and Safety of Intra-articular Injections of Frozen Platelet-Rich Plasma in Patients With Knee Osteoarthritis
NCT ID: NCT07329361
Last Updated: 2026-01-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
60 participants
INTERVENTIONAL
2025-12-16
2027-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Frozen Platelet-Rich Plasma
Platelet Rich Plasma
Platelet-rich plasma stored by freezing
Platelet-Rich Plasma
Platelet Rich Plasma
Fresh Platelet-Rich Plasma
Interventions
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Platelet Rich Plasma
Platelet-rich plasma stored by freezing
Platelet Rich Plasma
Fresh Platelet-Rich Plasma
Eligibility Criteria
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Inclusion Criteria
* Aged between 40 and 85 years old.
* Diagnosed with osteoarthritis through clinical radiological examination.
* Joint pain equal to or less than 75 points on the KOOS (pain).
* Radiological severity grades 1, 2, and 3 according to the Ahlbäck scale.
* Indication for intra-articular PRP infiltration.
* Body Mass Index values between 20 and 35.
* Negative serological tests for syphilis, HIV, HBV, and HCV.
* Possibility of observation during the follow-up period.
* Signature of informed consent.
Exclusion Criteria
* Diagnosed polyarticular disease.
* Previous arthroscopy in the last year.
* Severe mechanical deformity.
* Intra-articular hyaluronic acid injection in the last 12 months.
* Intra-articular corticosteroid or PRP injection in the last 6 months.
* Systemic autoimmune rheumatic disease (connective tissue diseases and systemic necrotizing vasculitis).
* Anemia or other hematological disorders.
* Positive serological tests for SYPHILIS, HIV, HBV, and HCV.
* Undergoing immunosuppressive treatments.
* Poorly controlled diabetes mellitus.
* Patients allergic to paracetamol.
* Pregnancy or breastfeeding.
40 Years
85 Years
ALL
No
Sponsors
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MiKS Hospital
OTHER
Responsible Party
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Locations
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Arthroscopic Surgery Unit, MiKS Hosptial
Vitoria-Gasteiz, Araba/Álava, Spain
Countries
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Facility Contacts
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Other Identifiers
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UCA-17/EC/25/CON
Identifier Type: -
Identifier Source: org_study_id
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