A Gray Zone Approach to Stroke Volume Variation Derived From NICOM

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2013-06-30

Study Completion Date

2014-05-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Optimal fluid management has been considered as crucial part to determine postoperative outcome and organ function. Recently developed, non invasive cardiac output measurement(NICOM, Cheetah Medical, Portland, OR)has enabled continuous cardiac output(CO) monitoring just by attaching electrode on chest wall. Moreover, CO and SSV derived from NICOM have been demonstrated as predictors of fluid responsiveness. Therefore, the aim of this study is to evaluate stroke volume variation derived from NICOM as a predictor of fluid responsiveness in neurosurgical patients. In addition, we plan to reveal inconclusive patients using gray zone approach.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Evaluation of SVV From NICOM as a Predictor of Fluid Responsiveness in Prone Position During Spine Surgery

NCT02277353

Fluid Responsiveness Prone Position Non Invasive Cardiac Output Monitoring

COMPLETED

Prediction of Fluid Responsiveness by NICOM (Non-invasive Cardiac Output Monitoring) in Children With Congenital Heart Disease After Cardiac Surgery

NCT01996956

Fluid Responsiveness

COMPLETED NA

Effect of Goal-directed Fluid Therapy Using Stroke Volume Variation in Patients Undergoing Free Flap Reconstruction After Head and Neck Cancer Resection

NCT02003066

General Anesthesia

COMPLETED NA

Stroke Volume Variation and Pulse Pressure Variation as Predictors of Fluid Responsiveness During Kidney Transplantation

NCT02459470

Kidney Transplantation

COMPLETED NA

Study About Predicting Fluid Responsiveness in Children Undergoing Neurosurgery

NCT01364103

Fluid Responsiveness

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Optimal fluid management has been considered as crucial part to determine postoperative outcome and organ function. Many reports have focussed on evaluation of fluid responsiveness using various parameters such as pulse pressure variation (PPV) or stroke volume variation (SSV) derived from invasive or semi-invasive monitoring. Recently developed, non invasive cardiac output measurement(NICOM, Cheetah Medical, Portland, OR)has enabled continuous cardiac output(CO) monitoring just by attaching electrode on thorax. Moreover, CO and SSV derived from NICOM have been demonstrated as predictors of fluid responsiveness. Therefore, the aim of this study is to evaluate stroke volume variation derived from NICOM as a predictor of fluid responsiveness in neurosurgical patients. In addition, we plan to reveal inconclusive patients using gray zone approach.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Neurological Diseases or Conditions Fluid Responsiveness Non Invasive Cardiac Output Monitoring Gray Zone

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

500ml fluid loading

All enrolled patients

500ml fluid loading

Intervention Type OTHER

Fluid loading to evaluate fluid responsiveness

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

500ml fluid loading

Fluid loading to evaluate fluid responsiveness

Intervention Type OTHER

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

500ml loading of crystalloid(Plasma Solution-A Injection CJ) over 15min at the end of operation, when the main procedure finished and there is no strong stimulation with stable hemodynamics

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* ASA I or ASA II patients aged 20-80 undergoing neurosurgery in supine position

Exclusion Criteria

* Pre-existing arrythmic disorders
* Congestive heart failure required medical treatment
* Preoperative Creatinine 1.3mg/dl
* observing self respiration during the study interventions
* Bleeding tendency
* Severe brain edema

Minimum Eligible Age

20 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No