Third Molar Clinical Trials: Pericoronitis Studies

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

115 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-01-31

Study Completion Date

2013-12-31

Brief Summary

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The purpose of this research study is to find out if the infection around 3rd molars and the resulting inflammation around the gum also produces a general systemic inflammation.

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Detailed Description

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Relate signs and symptoms of mild pericoronitis, an oral clinical condition characterized by intense inflammation and pain around a lower 3rd molar, to indicators of oral and systemic inflammation in patients seeking treatment for the condition.

Conditions

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Pericoronitis

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Mild Pericoronitis

Those with mild signs/symptoms of pericoronitis affecting at least one lower 3rd molar with adjacent 2nd molar will be monitored for 12 months following study entry or 3 months for those electing to have 3rd molar extraction.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Mild signs/symptoms of pericoronitis affecting at least one lower 3rd molar with adjacent 2nd molar (spontaneous pain with localized swelling, purulence/drainage) with recommended treatment being removal of 3rd molars,
* Age 18 - 35 years,
* ASA I, II health status,
* AAP 1-3 periodontal status,
* Willingness to participate in the study,
* Geographic proximity to UNC.

Exclusion Criteria

* Major signs/symptoms of pericoronitis (Temperature \>101 , dysphagia, limited mouth opening \<20mm incisor, facial swelling/cellulitis, severe uncontrolled discomfort),
* ASA III, IV health status,
* Medical contraindication to full mouth periodontal probing,
* AAP 4 periodontal status,
* Antibiotic treatment within the past 2 months,
* Current tobacco use,
* BMI \> 29,
* Pregnancy,
* Non English speaking.

Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes