Functional Correlates of Bipolar Disorders and Effects of the Psychoeducation. an fMRI Study

NCT ID: NCT01821469

Last Updated: 2014-01-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-05-31

Study Completion Date

2013-12-31

Brief Summary

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This research project follows two main objectives: 1) Assess anatomical and functional cerebral abnormalities in bipolar disorder. 2) Evaluate anatomical and functional changes after the application of a psychoeducational program in these patients. Specifically, this project aims to assess neurophysiological (fMRI - activation and functional connectivity) and neuroanatomical (morphometry and diffusion tensor imaging) specificities related to bipolar disorders and the therapeutic response to the psychoeducation. The results of this thesis project would also contribute to the validation of a pathophysiological model of the bipolar disorder.

Detailed Description

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Conditions

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Conditions Influencing Health Status Bipolar Disorders

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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psychoeducation

psychoeducation (12 weeks)

Group Type EXPERIMENTAL

psychoeducation

Intervention Type BEHAVIORAL

Bipolar disorders are educated to learn about their pathology

Interventions

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psychoeducation

Bipolar disorders are educated to learn about their pathology

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* clinical diagnosis of bipolar disorders
* euthymic (Montgomery and Asberg depression rating scale \< 10, Young Mania rating scale \< 10)

Exclusion Criteria

* other concomitant psychiatric disorders
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University Hospital, Grenoble

OTHER

Sponsor Role lead

Responsible Party

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AdministrateurDRC

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Thierry Bougerol, professor

Role: PRINCIPAL_INVESTIGATOR

CHU grenoble pôle psychiatrie et neurologie

Locations

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Ums Irmage

Grenoble, , France

Site Status

Countries

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France

References

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Favre P, Polosan M, Pichat C, Bougerol T, Baciu M. Cerebral Correlates of Abnormal Emotion Conflict Processing in Euthymic Bipolar Patients: A Functional MRI Study. PLoS One. 2015 Aug 5;10(8):e0134961. doi: 10.1371/journal.pone.0134961. eCollection 2015.

Reference Type DERIVED
PMID: 26244883 (View on PubMed)

Other Identifiers

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2011-A00425-36

Identifier Type: OTHER

Identifier Source: secondary_id

EssaiClinique_"BIP-ED"

Identifier Type: -

Identifier Source: org_study_id

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