Reduction of In-hospital Delays in Stroke Thrombolysis: SITS-WATCH

NCT ID: NCT01811901

Last Updated: 2013-03-15

Basic Information

• Recruitment Status: UNKNOWN
• Clinical Phase: NA
• Total Enrollment: 3000 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2013-01-31
• Study Completion Date: 2015-06-30

Brief Summary

In patients with acute ischemic stroke: the sooner the thrombolysis treatment is administered after symptom onset - the better the outcome. This delay can be dissected into onset-to-door time and door-to-needle time (DNT). SITS-WATCH aims to reduce median DNT in participating centres.

Detailed Description

In patients with acute ischemic stroke: the sooner the thrombolysis treatment is administered after symptom onset - the better the outcome. This delay can be dissected into onset-to-door time and door-to-needle time (DNT). Of the two, DNT can be directly influenced within the hospital by stream-lining of acute stroke care. The aim of our study is to reduce in-hospital delays (DNT) in self-selecting centers recruiting patients into the the Safe Implementation of Treatments in Stroke-International Stroke Thrombolysis Register (SITS-ISTR) , comprising currently more than 80 000 patients from 1338 centers. Current median of DNT in all SITS centers is 65 minutes (compared with 20 minutes in Helsinki Univer-sity Central Hospital). An itemized detailed questionnaire, including all factors known to influence DNT, has been sent to all SITS centers to identify the reasons for long in-hospital delays. Based on the replies, we have prepared a list of interventions that can be considered by individual SITS centers in order to reduce DNT with interventions that are in line with national legislation.

Conditions

Stroke

Study Design

• Allocation Method: NON_RANDOMIZED
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: HEALTH_SERVICES_RESEARCH
• Blinding Strategy: NONE

Study Groups

Intervention group (SITS-WATCH centers)

15-item list of suggested interventions aiming to reduce DNT sent to SITS-WATCH centers.

Group Type: ACTIVE_COMPARATOR

Reduction of DTN

Intervention Type: OTHER

15-item list of suggested interventions aiming to reduce DNT sent to SITS-WATCH centers.

Control group (non SITS-WATCH centers in SITS registry)

Centres that do not use 15-item list of suggested interventions aiming to reduce DNT.

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

Reduction of DTN

15-item list of suggested interventions aiming to reduce DNT sent to SITS-WATCH centers.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• All consecutive patients with acute ischemic stroke registered in SITS registry.

Exclusion Criteria

• Centers not inputing patient data into SITS registry. Patients with missing DNT data.

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

SITS International

NETWORK

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

SITS International / Karolinska Hospital

Stockholm, , Sweden

Site Status: RECRUITING

Countries

Sweden

Central Contacts

Nils Wahlgren, Prof.

Role: CONTACT

nils.wahlgren@karolinska.se

0046 8 517 75 600

Daniel Strbian, Dr.

Role: CONTACT

Daniel.Strbian@hus.fi

Facility Contacts

Nils Wahlgren, Prof.

Role: primary

nils.wahlgren@karolinska.se

0046851775606

Oksana Petersen

Role: backup

oksana@sitsinternational.org

0046765557885

Other Identifiers

20130215

Identifier Type: -

Identifier Source: secondary_id

20130214

Identifier Type: -

Identifier Source: org_study_id