Long-term Outcome of RIPC After IV Thrombolysis in AIS Patients
NCT ID: NCT05614401
Last Updated: 2023-02-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
62 participants
OBSERVATIONAL
2022-10-28
2023-01-30
Brief Summary
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* Dose the RIPC treatment combined with IV thrombolysis can improve the long-term functional outcome in AIS patients?
* Dose the RIPC treatment combined with IV thrombolysis can improve the incidence rates of all-cause and cardiovascular mortality, recurrent stroke/TIA, new-onset clinical AF on this long-term follow-up? A single rater (A.E.P.) trained by an experienced stroke physician (S.T.E.) contacted patients, relatives, and family physicians to gather all available medical information on the following issues: 1) survival status, 2) date of death in those who died (based on information of the treating physicians), 3) mRS score at the time of the interview, 4) recurrent stroke/TIA, 5) new onset atrial fibrillation, 6) other cardiovascular events, including myocardial infarction, pulmonary embolism, deep venous thrombosis, peripheral arteriopathy.
Researchers will compare RIPC group and control group to see if the RIPC treatment have a long-term effect in AIS patients.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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RIPC group
Patients underwent RIPC treatment after IV thrombolysis in the index stroke.
functional and medical information
1\) functional outcomes(mRS scoring), 2)survival status, 3) date of death in those who died (based on information of the treating physicians), 3) mRS score at the time of the interview, 4) recurrent stroke/TIA, 5) new onset atrial fibrillation, 6) other cardiovascular events, including myocardial infarction, pulmonary embolism, deep venous thrombosis, peripheral arteriopathy.
Control group
The control group underwent no inflations or deflations in the index stroke.
functional and medical information
1\) functional outcomes(mRS scoring), 2)survival status, 3) date of death in those who died (based on information of the treating physicians), 3) mRS score at the time of the interview, 4) recurrent stroke/TIA, 5) new onset atrial fibrillation, 6) other cardiovascular events, including myocardial infarction, pulmonary embolism, deep venous thrombosis, peripheral arteriopathy.
Interventions
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functional and medical information
1\) functional outcomes(mRS scoring), 2)survival status, 3) date of death in those who died (based on information of the treating physicians), 3) mRS score at the time of the interview, 4) recurrent stroke/TIA, 5) new onset atrial fibrillation, 6) other cardiovascular events, including myocardial infarction, pulmonary embolism, deep venous thrombosis, peripheral arteriopathy.
Eligibility Criteria
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Inclusion Criteria
18 Years
ALL
No
Sponsors
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First Affiliated Hospital Xi'an Jiaotong University
OTHER
Responsible Party
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Principal Investigators
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Guoliang Li
Role: PRINCIPAL_INVESTIGATOR
First Affiliated Hospital of Xian Jiaotong University
Locations
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First Affiliated Hospital of Xian Jiantong University
Xi'an, Shaanxi, China
Countries
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References
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An J, Wei M, Wang D, Zhao C, Yuan X, Kimberly WT, Luo G, Li G. Long-term efficacy of remote ischaemic postconditioning after rt-PA intravenous thrombolysis in patients with acute ischaemic stroke. BMJ Open. 2025 Oct 28;15(10):e094001. doi: 10.1136/bmjopen-2024-094001.
Other Identifiers
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XJTU1AF2022LSK-407
Identifier Type: -
Identifier Source: org_study_id
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