Chinese Acute Ischemic Stroke Treatment Outcome Registry

NCT ID: NCT02470624

Last Updated: 2015-10-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

10000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-05-31

Study Completion Date

2017-03-31

Brief Summary

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This is a multi-center registry study. The investigators will include 10,000 patients with confirmed acute ischemic stroke in China. The aim of the study is to survey current treatment situation in China and compare the effectiveness and safety between different intervention regimens.

Detailed Description

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Stroke is a common disease in China. Compared to western countries, there are many treatment regimens used in clinical practice in China. But their treatment effects are not well validated. The aim of the study is to survey current treatment situation in China and compare the effectiveness and safety between different intervention regimens.

Conditions

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Ischemic Stroke

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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treatment following current guideline

treatment following current guideline

Intervention Type OTHER

Interventions

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treatment following current guideline

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. age ≥18 yesrs
2. confirmed diagnosis of an ischemic stroke
3. admission within 1 week after onset of stroke or within treatment time window for patients of thrombolysis treatment
4. signed informed consent

Exclusion Criteria

1. with intracerebral hemorrhage
2. with severe morbid (estimated survival duration less than 3 months)
3. could not provide follow-up information
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Techpool Bio-Pharma Co., Ltd.

INDUSTRY

Sponsor Role collaborator

Peking University First Hospital

OTHER

Sponsor Role lead

Responsible Party

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Yining Huang

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Yining Huang, MD

Role: PRINCIPAL_INVESTIGATOR

Peking University First Hospital

Locations

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Peking University First Hospital

Beijing, , China

Site Status RECRUITING

Countries

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China

Central Contacts

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Yining Huang, MD

Role: CONTACT

+86(10)83572857

Facility Contacts

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Yining Huang, MD

Role: primary

+86(10)83572857

References

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Huang D, Lu Y, Sun W, Sun W, Sun Y, Huang Y, Song Y, Tai L, Li G, Chen H, Zhang G, Zhang L, Sun X, Qiu J, Wei Y, Jin H. Functional Outcomes of Human Urinary Kallindinogenases in Treatment of Acute Ischemic Stroke. Stroke. 2025 Sep 29. doi: 10.1161/STROKEAHA.124.050188. Online ahead of print.

Reference Type DERIVED
PMID: 41017461 (View on PubMed)

Lu Y, Sun W, Huang Y, Wang Z, Shen Z, Sun W, Liu R, Li F, Shu J, Peng Q, Jia J, Sun P, Song Y, Jin H; CASTOR Investigators. Comparison of Factors Affecting Quality of Life in Patients with Acute Ischemic Stroke Across Different Stroke Severities. Neurol Ther. 2025 Jun;14(3):1023-1038. doi: 10.1007/s40120-025-00743-9. Epub 2025 Apr 29.

Reference Type DERIVED
PMID: 40301282 (View on PubMed)

Wang L, Guan X, Zhou J, Hu H, Liu W, Wei Q, Huang Y, Sun W, Jin X, Li H. Measuring the health outcomes of Chinese ischemic stroke patients based on the data from a longitudinal multi-center study. Qual Life Res. 2025 Jul;34(7):1967-1977. doi: 10.1007/s11136-025-03957-4. Epub 2025 Mar 27.

Reference Type DERIVED
PMID: 40146503 (View on PubMed)

Lu Y, Sun P, Jin H, Wang Z, Shen Z, Sun W, Sun Y, Liu R, Li F, Shu J, Qiu Z, Lu Z, Sun W, Zhu S, Huang Y; CASTOR Investigators. Prolonged Hospital Length of Stay Does Not Improve Functional Outcome in Acute Ischemic Stroke. Neurol Ther. 2025 Apr;14(2):593-607. doi: 10.1007/s40120-025-00712-2. Epub 2025 Feb 18.

Reference Type DERIVED
PMID: 39964661 (View on PubMed)

Li Y, Ou Q, Lu Y, Shen Z, Li J, Zhang Z, Tai L, Li G, Chen H, Zhang G, Zhang L, Sun X, Qiu J, Wei Y, Zhu S, Wang Z, Sun W, Huang Y. Geographic differences in pharmacotherapy patterns and outcomes of acute ischemic stroke in China. BMC Neurol. 2024 Feb 15;24(1):64. doi: 10.1186/s12883-024-03564-9.

Reference Type DERIVED
PMID: 38360588 (View on PubMed)

Sun W, Ou Q, Zhang Z, Qu J, Huang Y. Chinese acute ischemic stroke treatment outcome registry (CASTOR): protocol for a prospective registry study on patterns of real-world treatment of acute ischemic stroke in China. BMC Complement Altern Med. 2017 Jul 6;17(1):357. doi: 10.1186/s12906-017-1863-4.

Reference Type DERIVED
PMID: 28683732 (View on PubMed)

Other Identifiers

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Neurology-stroke

Identifier Type: -

Identifier Source: org_study_id

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