Hemodynamic in Postreperfusion Period and Functional Recovery in Acute Ischemic Stroke Patients
NCT ID: NCT05517109
Last Updated: 2024-10-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
90 participants
INTERVENTIONAL
2022-03-12
2024-08-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
NONE
Study Groups
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Control group. Standart care
Standart hemodynamic goals: systolic blood pressure 160-185 mmHg in first 24 hours after intravenous thrombolysis
No interventions assigned to this group
Systolic blood pressure ≤ 160 mmHg
Lower hemodynamic goals: systolic blood pressure ≤ 160 mmHg in first 24 hours after intravenous thrombolysis
Hemodynamic goal including lower goal of systolic blood pressure
Different hemodynamic goals in different study arms
Interventions
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Hemodynamic goal including lower goal of systolic blood pressure
Different hemodynamic goals in different study arms
Eligibility Criteria
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Inclusion Criteria
* performed intravenous thrombolysis (including "wake up stroke")
* systolic blood pressure \>140 mmHg
* informed consent or council of physician agreement
Exclusion Criteria
* pregnancy
* patients participainting in other clinical trial in the last 90 days
* any absolute contraindications to intravenous thrombolysis
Сompletion criteria:
* failure to achieve hemodynamic goal for 20 minutes before the start of intravenous thrombolysis
* failure to achieve hemodynamic goal for 60 minutes in first 24 hours after intravenous thrombolysis
* relative arterial hypotension (SBP \<100 mmHg for 60 minutes in first 24 hours after intravenous thrombolysis)
* unfavorable effect development (e.g. seizures, angioedema)
* informed consent is retracted
18 Years
ALL
No
Sponsors
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Northern State Medical University
OTHER
Responsible Party
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Principal Investigators
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Mikhail Kirov, PhD
Role: STUDY_DIRECTOR
Northen state medical university
Alexey Avidzba
Role: STUDY_CHAIR
Northen state medical university
Locations
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City Hospital # 1 n.a. E.E. Volosevich
Arkhangelsk, , Russia
Countries
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Other Identifiers
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IVT-160
Identifier Type: -
Identifier Source: org_study_id
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