EtCO2 Monitoring in Acute Self-poisoning

NCT ID: NCT01800123

Last Updated: 2013-02-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-03-31

Brief Summary

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There is no consensus on monitoring criteria in acute self poisoning. Clinical scores, vital signs or lactatemia have failed to prove good predictive value.

The main acute self poisoning complication is decreased consciousness level with consequent increased risk of hypoxemia and aspiration pneumonitis.

Several clinical studies have recently shown that EtCO2 monitoring can be valuable in procedural sedation in the emergency department. It is able to predict hypoxemia before any SaO2 decrease and any complications related to these procedures.

We therefore hypothesized that EtCO2 could help in acute self poisoning patients' monitoring in the ED.

Detailed Description

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Conditions

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Acute Intentional Overdose

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Acute poisoning

Consecutive acute drug self poisoned patients admitted in the ED.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* \>18y/o
* acute self poisoning patients
* patients requiring monitoring according to physician's opinion
* patients not requiring invasive ventilation at ED admission

Exclusion Criteria

* Pregnant woman
* patients deprived of liberty
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Grenoble

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Genoble university hospital

Grenoble, , France

Site Status RECRUITING

Countries

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France

Facility Contacts

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Maxime Maignan, MD

Role: primary

33 4 76 76 59 34

References

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Viglino D, Bourez D, Collomb-Muret R, Schwebel C, Tazarourte K, Dumanoir P, Paquier C, Danel V, Debaty G, Maignan M. Noninvasive End Tidal CO2 Is Unhelpful in the Prediction of Complications in Deliberate Drug Poisoning. Ann Emerg Med. 2016 Jul;68(1):62-70.e1. doi: 10.1016/j.annemergmed.2015.11.037. Epub 2016 Jan 23.

Reference Type DERIVED
PMID: 26810758 (View on PubMed)

Other Identifiers

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2011-14

Identifier Type: -

Identifier Source: org_study_id

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