Evaluation of the Role of Poisoning Severity Score, Serum Procalcitonin and C-reactive Protein in Acute Hydrocarbon Intoxicated Cases Admitted to the Poison Control Center Ain Shams University Hospitals
NCT ID: NCT06151301
Last Updated: 2023-11-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
60 participants
OBSERVATIONAL
2023-12-01
2024-12-01
Brief Summary
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They are derived mainly from petroleum (kerosene, gas, naphtha) or wood (turpentine, pine oil). They can be found in liquid, gas, or solid form depending on their properties. All hydrocarbons can be toxic, but aromatic (ring-shaped) and halogenated hydrocarbons typically have more severe toxicity .
Toxicity occurs in various ways including through inhalation, ingestion, aspiration, and dermal exposure. Frequently, these exposures occur during attempted recreational use of the substances and sometimes for self-injurious behavior
Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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control group
20 subjects of apparently healthy persons for estimating the standard levels of the tested biomarkers.
serum procalcitonin
predicting the severity of intoxication
C-reactive protein
predicting the severity of intoxication
case group
60 patients divided into mild, moderate and severe toxicity according to the poisoning severity score.
serum procalcitonin
predicting the severity of intoxication
C-reactive protein
predicting the severity of intoxication
Interventions
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serum procalcitonin
predicting the severity of intoxication
C-reactive protein
predicting the severity of intoxication
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Cases \> 24 hours of intoxication.
* Cases with occupational exposure to hydrocarbons.
* Pregnant females.
* Any cases received any treatment before arrival to the PCC.
* Cases suffering from cardiac, respiratory, renal, hepatic or haematological disorders.
* Cases presenting with fever.
* Cases with other causes that can increase levels of CRP \& pro-calcitonin as bacterial infection, recent major trauma, major burn ,septic shock and medullary thyroid cancer.
ALL
No
Sponsors
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Sohag University
OTHER
Responsible Party
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Mera Gergis khalil
assistant lecteurer Forensic medicine and Toxicology department sohag univerisity hospital
Locations
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Ain Shams university Hospital
Cairo, , Egypt
Countries
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Central Contacts
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Maha A Helal, professor
Role: CONTACT
Facility Contacts
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Gehan B Azab, professor
Role: primary
Other Identifiers
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Soh-Med-23-11-01MD
Identifier Type: -
Identifier Source: org_study_id