Effects of Low-level Laser Therapy on Global Gene Expression of Young Males Submitted to Physical Strength Training

NCT ID: NCT01784432

Last Updated: 2013-02-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-01-31

Study Completion Date

2012-09-30

Brief Summary

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Muscle performance is largely influenced by modulations in gene expressions of muscle tissue. In this context, low-level laser therapy has been used to improve muscle performance in experimental models and human researches. Thereby, the investigators examined modulations on global gene expression of muscle tissue influenced by exercise associated to low-level laser therapy.

Detailed Description

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This study assessed muscle performance in isokinetic dynamometry and leg press device; global gene expression of muscle tissue by microarray analysis

Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Low-level laser therapy and training

Effects of low-level laser therapy on muscle performance during physical strength training and gene expression of muscle tissue.

Group Type ACTIVE_COMPARATOR

Low-level laser therapy and training

Intervention Type DEVICE

Training without low-level laser therapy

Effects of physical strength training without low-level laser therapy on muscle performance and gene expression of muscle tissue

Group Type ACTIVE_COMPARATOR

Training

Intervention Type OTHER

Interventions

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Low-level laser therapy and training

Intervention Type DEVICE

Training

Intervention Type OTHER

Other Intervention Names

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Laser Laser therapy Low-level laser therapy

Eligibility Criteria

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Inclusion Criteria

* healthy males aged between 18 and 28 years;
* body mass index (BMI) equal to or less than 26 kg/m2;
* moderated pattern of physical activity

Exclusion Criteria

* previous injury to the femoral quadriceps or hamstring muscles (within 6 months prior to study),
* osseous or articular disorder in the lower limbs,
* cardiovascular system disorders,
* systemic disease, and
* taking prescription medicines or using dietary supplements such as muscle mass builders
Minimum Eligible Age

18 Years

Maximum Eligible Age

28 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Fundação de Amparo à Pesquisa do Estado de São Paulo

OTHER_GOV

Sponsor Role collaborator

Centro de Pequisas de Ótica e Fotônica

OTHER

Sponsor Role collaborator

Faculty of Medicine of Ribeirão Preto (FMRP-USP)

OTHER

Sponsor Role collaborator

Fundação Hemocentro de Ribeirão Preto

UNKNOWN

Sponsor Role collaborator

Universidade Federal de Sao Carlos

OTHER

Sponsor Role lead

Responsible Party

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Cleber Ferraresi

MSc

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Cleber Ferraresi, MSc

Role: PRINCIPAL_INVESTIGATOR

Universidade Federal de Sao Carlos

Nivaldo A Parizotto, PhD

Role: STUDY_DIRECTOR

Universidade Federal de Sao Carlos

Vanderlei S Bagnato, PhD

Role: STUDY_DIRECTOR

University of Sao Paulo

Locations

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Federal University of São Carlos

São Carlos, São Paulo, Brazil

Site Status

Countries

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Brazil

References

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Ferraresi C, de Brito Oliveira T, de Oliveira Zafalon L, de Menezes Reiff RB, Baldissera V, de Andrade Perez SE, Matheucci Junior E, Parizotto NA. Effects of low level laser therapy (808 nm) on physical strength training in humans. Lasers Med Sci. 2011 May;26(3):349-58. doi: 10.1007/s10103-010-0855-0. Epub 2010 Nov 18.

Reference Type BACKGROUND
PMID: 21086010 (View on PubMed)

Vieira WH, Ferraresi C, Perez SE, Baldissera V, Parizotto NA. Effects of low-level laser therapy (808 nm) on isokinetic muscle performance of young women submitted to endurance training: a randomized controlled clinical trial. Lasers Med Sci. 2012 Mar;27(2):497-504. doi: 10.1007/s10103-011-0984-0. Epub 2011 Aug 26.

Reference Type BACKGROUND
PMID: 21870127 (View on PubMed)

Other Identifiers

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CAAE: 0150.0.135.000-10

Identifier Type: -

Identifier Source: org_study_id

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