Effect of Low-level Laser Therapy on Exercise-induced Muscle Damage

NCT ID: NCT02493556

Last Updated: 2015-10-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

12 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-06-30

Study Completion Date

2015-09-30

Brief Summary

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Introduction: The effects of Low Level Laser Therapy (LLLT) on exercise-induced muscular damage have been studied over the last years. Studies have been conducted on animals and humans in order to try to show the benefits of the intervention, but there is still conflicting evidence about its protective and therapeutic effects.

Objectives: To describe the effects of LLLT on pain, strength and muscular inflammation after plyometric exercise.

Methods: A randomized, double-blinded, placebo-controlled trial with participation of 20 male healthy volunteers will be performed. Healthy and physically active individuals, aged between 18 and 35 years, with no history of injury on the lower limbs or contra-indications to maximal exercise performance will be included. A protocol of 10 series with 10 repetitions of the countermovement jump will be used to induce muscle damage at the lower limbs. Immediately before or after the exercise protocol, LLLT will be applied on one lower limb, while the other will receive placebo treatment. Phototherapy will be applied with an equipment of 810nm and a cluster with 5 diodes on 8 different points of the knee extensor muscle, totalizing a dosage of 240J. The placebo treatment will be held on the same way, but the equipment will be turned off. The volunteers will be evaluated at baseline (before the exercise protocol) and at follow-up of 24, 48 and 72 hours. The following outcomes will be evaluated: knee extensors isometric peak torque by Isokinetic Dynamometer, pain by Visual Analogue Scale and muscular tissue echo intensity by Ultrasonography.

Detailed Description

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Conditions

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Muscle Damage

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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LLLT before muscle damage

Low Level Laser Therapy (LLLT) will be applied before the exercise protocol on one lower limb, while the other will receive placebo treatment. Phototherapy will be applied with an equipment of 810nm and a cluster with five diodes on eight different points of quadriceps muscle, totalizing a dosage of 240J.

Group Type EXPERIMENTAL

LLLT before muscle damage

Intervention Type DEVICE

Placebo LLLT before muscle damage

Placebo LLLT will be applied before the exercise protocol on one lower limb, while the other will receive real treatment. Placebo treatment will also be applied on eight different points of quadriceps muscle, but the equipment will be turned off.

Group Type PLACEBO_COMPARATOR

Placebo LLLT before muscle damage

Intervention Type DEVICE

LLLT after muscle damage

Low Level Laser Therapy (LLLT) will be applied after the exercise protocol on one lower limb, while the other will receive placebo treatment. Phototherapy will be applied with an equipment of 810nm and a cluster with five diodes on eight different points of quadriceps muscle, totalizing a dosage of 240J.

Group Type ACTIVE_COMPARATOR

LLLT after muscle damage

Intervention Type DEVICE

Placebo LLLT after muscle damage

Placebo LLLT will be applied after the exercise protocol on one lower limb, while the other will receive real treatment. Placebo treatment will also be applied on eight different points of quadriceps muscle, but the equipment will be turned off.

Group Type PLACEBO_COMPARATOR

Placebo LLLT after muscle damage

Intervention Type DEVICE

Interventions

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LLLT before muscle damage

Intervention Type DEVICE

Placebo LLLT before muscle damage

Intervention Type DEVICE

LLLT after muscle damage

Intervention Type DEVICE

Placebo LLLT after muscle damage

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Healthy males aged between 18 and 35 years;
* Sedentary or physically active individuals who exercise up to 3 times per week.

Exclusion Criteria

* Individuals who participate in systematic exercise training;
* Individuals who participate in strength training for the lower limbs;
* Individuals with lower or upper limb injuries;
* Individuals with contra-indications to maximal exercise performance (due to neurological, cardiovascular or respiratory conditions);
* Individuals who show difficulties to understand the study protocol.
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Federal University of Health Science of Porto Alegre

OTHER

Sponsor Role lead

Responsible Party

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Bruno Manfredini Baroni

Phd

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Bruno Baroni, phD

Role: STUDY_DIRECTOR

Federal University of Health Science of Porto Alegre

Locations

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Federal University of Health Science of Porto Alegre

Porto Alegre, Rio Grande do Sul, Brazil

Site Status

Countries

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Brazil

Other Identifiers

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38076514.0.0000.5345

Identifier Type: -

Identifier Source: org_study_id

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