Influence of PBM on Anaerobic Capacity Under Normoxia and Hypoxia

NCT ID: NCT05595564

Last Updated: 2022-10-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

7 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-08-31

Study Completion Date

2022-12-31

Brief Summary

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The photobiomodulation (PBM) shows positive results in muscle performance, fatigue reduction, management of blood lactate production, analgesia and in the increase of VO2 maximal, favoring the increase of ATP production and thus the energy metabolism. The association of PBM applied before high-intensity treadmill training shows physiological improvements both in normoxic (Nor) and hypoxic (Hip) conditions. Anaerobic capacity (AC) is the maximum amount of ATP that can be resynthesized by anaerobic metabolism and is an important predictor of high-intensity exercise since an athlete's ability to perform efforts to increase maximal oxygen consumption (VO2max) depends on AL. In view of the above information the main objective of the present research project will be to investigate the effects of PBM on AC under normoxic and hypoxic conditions in amateur runners. To test the effects of exercise training on anaerobic capacity under normoxic and hypoxic conditions, 7 individuals will be randomly submitted to four maximal efforts to exhaustion with intensity corresponding to 110% of VO2max in Hip, Nor, Hip+Ebio and Nor+Ebio conditions. These efforts will be used to estimate the AC, that is, the maximum accumulated deficit of alternative oxygen (MAODRED), from the sum of the energy contribution of the anaerobic and lactic metabolisms.

Detailed Description

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Conditions

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Low Level Laser Therapy Photobiomodulation Performance Sport

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Hypoxia

Participant developed running activity on a treadmill in hypoxic condition, submitted or not to photobiomodulation therapy.

Group Type EXPERIMENTAL

Photobiomodulation therapy

Intervention Type DEVICE

A previous application of photobiomodulation therapy was offered or not, for possible performance enhancement.

Normoxia

Participant developed treadmill running activity in normoxic condition, submitted or not to photobiomodulation therapy.

Group Type ACTIVE_COMPARATOR

Photobiomodulation therapy

Intervention Type DEVICE

A previous application of photobiomodulation therapy was offered or not, for possible performance enhancement.

Interventions

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Photobiomodulation therapy

A previous application of photobiomodulation therapy was offered or not, for possible performance enhancement.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* healthy individuals
* VO2 maximal equal to or greater than 34 ml/kg.min
* capacity for physical activity according to the PAR-Q questionnaire

Exclusion Criteria

* musculoskeletal injury in the last three months;
* cardiovascular diseases;
* use of anabolic, anti-inflammatory and analgesic drugs 72 hours before the evaluations;
* use of alcohol and illicit drugs during the collection period;
Minimum Eligible Age

18 Years

Maximum Eligible Age

29 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Sao Paulo

OTHER

Sponsor Role lead

Responsible Party

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Rinaldo Roberto de Jesus Guirro

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Carlos E Girasol, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Sao Paulo

Locations

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University of Sao Paulo

Ribeirão Preto, São Paulo, Brazil

Site Status

Countries

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Brazil

References

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Ferraresi C, Beltrame T, Fabrizzi F, do Nascimento ES, Karsten M, Francisco Cde O, Borghi-Silva A, Catai AM, Cardoso DR, Ferreira AG, Hamblin MR, Bagnato VS, Parizotto NA. Muscular pre-conditioning using light-emitting diode therapy (LEDT) for high-intensity exercise: a randomized double-blind placebo-controlled trial with a single elite runner. Physiother Theory Pract. 2015 Jul;31(5):354-61. doi: 10.3109/09593985.2014.1003118. Epub 2015 Jan 14.

Reference Type BACKGROUND
PMID: 25585514 (View on PubMed)

Ando S, Komiyama T, Sudo M, Higaki Y, Ishida K, Costello JT, Katayama K. The interactive effects of acute exercise and hypoxia on cognitive performance: A narrative review. Scand J Med Sci Sports. 2020 Mar;30(3):384-398. doi: 10.1111/sms.13573. Epub 2019 Oct 27.

Reference Type BACKGROUND
PMID: 31605635 (View on PubMed)

Other Identifiers

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Hypoxia_PBM

Identifier Type: -

Identifier Source: org_study_id

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