Comparison of Standard Versus Low Bicarbonate Hemodialysis

NCT ID: NCT01777178

Last Updated: 2019-04-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-01-31

Study Completion Date

2013-06-30

Brief Summary

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This study will compare acid-base changes during hemodialysis treatments with a standard dialysis bath versus a lower bicarbonate dialysis bath, and aims to define the factors that limit equilibration of the bicarbonate concentration in a patient's blood with that in the dialysate.

Detailed Description

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Conditions

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Chronic Kidney Disease Metabolic Acidosis

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Low bicarbonate dialysis

Group Type EXPERIMENTAL

Low bicarbonate dialysis

Intervention Type OTHER

Interventions

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Low bicarbonate dialysis

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Receiving chronic thrice-weekly conventional hemodialysis for at least 3 months
* Age \> 18 years

Exclusion Criteria

* Use of oral alkali within the previous month
* Hospitalization within the previous month
* Inability to provide written informed consent
* Pregnancy
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Albert Einstein College of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Matthew Abramowitz

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Matthew K Abramowitz, MD, MS

Role: PRINCIPAL_INVESTIGATOR

Albert Einstein College of Medicine

Locations

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Montefiore Medical Center/Jack D. Weiler Hospital

The Bronx, New York, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Informed Consent Form

View Document

Other Identifiers

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2012-684

Identifier Type: -

Identifier Source: org_study_id

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