Retinal Venous Pressure and ET-1 in Patients With Diabetes Mellitus
NCT ID: NCT01771835
Last Updated: 2013-01-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
20 participants
OBSERVATIONAL
2011-08-31
2012-11-30
Brief Summary
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Detailed Description
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In ocular blood flow perfusion pressure plays an important role. While in healthy eyes a spontaneous retinal venous pulsation is frequently observed, this is significantly less frequent in diseased eyes. An increased venous pressure lowers the ocular perfusion pressure, and increases the transmural pressure. A measurement of the retinal venous pressure and the hormone ET-1 in the blood will give us a better knowledge of the circulatory changes and their relationship to diabetes.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Diabetes patients
Patients with diabetes mellitus type I + II, without diabetic retinopathy
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* no diabetic retinopathy
Exclusion Criteria
* acute or chronic inflammation of the eyes
* narrow angle glaucoma
* minority
18 Years
ALL
No
Sponsors
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University Hospital, Basel, Switzerland
OTHER
Responsible Party
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Principal Investigators
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Josef Flammer, MD
Role: STUDY_DIRECTOR
University of Basel, Dept. of Ophthalmology
Locations
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University of Basel, Dept. of Ophthalmology
Basel, , Switzerland
Countries
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References
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Cybulska-Heinrich AK, Baertschi M, Loesche CC, Schoetzau A, Konieczka K, Josifova T, Flammer J. Patients with diabetic retinopathy have high retinal venous pressure. EPMA J. 2015 Feb 24;6(1):5. doi: 10.1186/s13167-015-0027-1. eCollection 2015.
Other Identifiers
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089-CYA-2012
Identifier Type: -
Identifier Source: org_study_id
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