Detection of Vascular Injury in Diabetes Through Eye and Nailfold Data (DIVIDEND) - A Pilot Study
NCT ID: NCT01279928
Last Updated: 2011-01-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
26 participants
OBSERVATIONAL
2010-03-31
2010-10-31
Brief Summary
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It was hypothesized that in a paediatric population with type 1 diabetes mellitus the novel investigations would be associated with small blood vessel disease and that widespread changes to these blood vessels would be detected through associations between the different novel investigations.
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Detailed Description
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Conditions
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Study Design
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CROSS_SECTIONAL
Study Groups
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Type 1 Diabetes Paediatric
Paediatric patients aged 8-18 with diagnosed Diabetes Mellitis Type 1 attending paediatric clinic at John Hunter Hospital.
Video Nailfold Capillaroscopy
Single session of video Nailfold Capillaroscopy wit KKK technology
Ambulatory 24 hr Blood Pressure Monitoring
24 hr upper arm cuff measurement of Blood Pressure
Fundoscopy of eyes
examination of microvascular health of eye with the use of opthalmoscope
Laser Doppler Flowmetry
Examination of vascular flow
Interventions
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Video Nailfold Capillaroscopy
Single session of video Nailfold Capillaroscopy wit KKK technology
Ambulatory 24 hr Blood Pressure Monitoring
24 hr upper arm cuff measurement of Blood Pressure
Fundoscopy of eyes
examination of microvascular health of eye with the use of opthalmoscope
Laser Doppler Flowmetry
Examination of vascular flow
Eligibility Criteria
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Inclusion Criteria
* Have a diagnosis of type 1 diabetes mellitus
Exclusion Criteria
* Significant autoimmune rheumatological disease (e.g. lupus or dermatomyositis)
8 Years
18 Years
ALL
No
Sponsors
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John Hunter Hospital
OTHER_GOV
Responsible Party
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John Hunter Hospital
Principal Investigators
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Rani Bhatia, MD
Role: PRINCIPAL_INVESTIGATOR
John Hunter Children's Hospital
Locations
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John Hunter Children's Hospital
New Lambton, New South Wales, Australia
Countries
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References
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Hosking SP, Bhatia R, Crock PA, Wright I, Squance ML, Reeves G. Non-invasive detection of microvascular changes in a paediatric and adolescent population with type 1 diabetes: a pilot cross-sectional study. BMC Endocr Disord. 2013 Oct 5;13:41. doi: 10.1186/1472-6823-13-41.
Other Identifiers
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HNEHREC 09/04/15/5.10
Identifier Type: -
Identifier Source: org_study_id
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