The Effect of Laser-assisted Zona Thinning on the Implantation Rate in the Women of Advanced Age
NCT ID: NCT01765322
Last Updated: 2013-11-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
150 participants
INTERVENTIONAL
2013-11-30
2015-07-31
Brief Summary
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Detailed Description
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1. It's required to sign an informed consent form prior to the recruitment of all patients.
2. Data collection and entry need double check and supervision.
The outcome measures:
the implantation rate per embryo transfer miscarriage live birth
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Assisted hatching group (AH group)
The subjects are going to participate the treatment of assisted hatching in vitro fertilization by Zona Infrared Laser Optical System (ZILOS-TK IVOS Analyzer,Hamilton Thorne Biosciences,USA).
ZILOS-TK IVOS Analyzer
The subjects are going to participate the treatment of assisted hatching in vitro fertilization by Zona Infrared Laser Optical System (ZILOS-TK,Hamilton Thorne Biosciences,USA)
Control group
The subjects are going to undergo the same procedure except for the treatment of assisted hatching.
No interventions assigned to this group
Interventions
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ZILOS-TK IVOS Analyzer
The subjects are going to participate the treatment of assisted hatching in vitro fertilization by Zona Infrared Laser Optical System (ZILOS-TK,Hamilton Thorne Biosciences,USA)
Eligibility Criteria
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Inclusion Criteria
* Basal FSH value: FSH≤10IU/L
* Day-3 embryos transferred in the fresh IVF/ICSI cycles
* the number of embryos available to be transferred on Day-3: ≥one embryo
Exclusion Criteria
* cycles with oocyte donation transfer.
* the maximum number of previous unsuccessful IVF attempts: ≥ 3 cycles(transfer cycles)
* any cycles with the risk of OHSS, fluid in the uterine cavity, abnormal endometrium, uterine abnormalities,pelvic inflammation, and other acute maternal problems.
* One or both spouses have an abnormal karyotype (including polymorphism)
35 Years
46 Years
FEMALE
No
Sponsors
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Shanxi Provincial Maternity and Children's Hospital
OTHER
Responsible Party
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Shi Wenhao
Assisted Reproductive Technology Center
Principal Investigators
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Wenhao Shi, Master
Role: STUDY_DIRECTOR
Maternal and Children Health Care Hospital
Locations
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Maternal and Children Health Care Hospital
Xi'an, Shaanxi, China
Countries
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Central Contacts
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Facility Contacts
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Wenhao Shi, Master
Role: primary
Other Identifiers
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MCHC-2013-01
Identifier Type: -
Identifier Source: org_study_id