Transcriptome Profiling and Endometrial Receptivity

NCT ID: NCT03925311

Last Updated: 2025-03-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

220 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-04-20

Study Completion Date

2025-12-31

Brief Summary

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The aim of this study is to correlate and identify the biochemical markers which may reflect WOI. Blood samples will be collected and endometrial biopsy will be performed at particular time points.

Detailed Description

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Endometrial receptivity in the midluteal phase of the menstrual cycle, known as the window of implantation (WOI), occurs only for a very short period of time. However, so far, there is no reliable clinical and biochemical indicators of WOI. Therefore, this study is to correlate and identify the biochemical markers which may reflect WOI.

participants will be asked to be:

1. performed endometrial biopsy
2. taken blood for a few time points (e.g. pre-conception and being pregnant) and to compare different kinds of biochemical markers.

Conditions

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Pregnancy Related

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Interventions

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endometrial biopsy and blood sampling

patient will be performed endometrial biopsy and collected blood samples at particular time points

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

Age 20-40 years.

Exclusion Criteria

* Uncorrected uterine anomalies, such as septate or bicornuate uterus, fibroids (submucous/intramural).
* Intrauterine adhesions.
* Adenomyosis.
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Chinese University of Hong Kong

OTHER

Sponsor Role lead

Responsible Party

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Chung Pui Wah Jacqueline

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Pui Wah Jacqueline Chung, MBBS

Role: PRINCIPAL_INVESTIGATOR

Chinese University of Hong Kong

Locations

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Chinese University of Hong Kong

Hong Kong, , Hong Kong

Site Status RECRUITING

Countries

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Hong Kong

Central Contacts

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Hiu Tan Margaret Lee

Role: CONTACT

85235051764

Pui Wah Jacqueline Chung, MBBS

Role: CONTACT

85235051764

Facility Contacts

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Hiu Tan Margaret Lee

Role: primary

(852)35051764

Pui Wah Jacqueline Chung, MBBS

Role: backup

(852)35051764

Other Identifiers

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2014.637

Identifier Type: -

Identifier Source: org_study_id

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