Computerised Assessment of Visual Neglect Symptoms in Peripersonal Space

NCT ID: NCT01740544

Last Updated: 2018-11-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-10-31

Study Completion Date

2012-12-31

Brief Summary

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Healthy subjects will undergo cathodal stimulation of the right posterior parietal Cortex (PPC) and assessment of neglect-like symptoms in the encircling monitor system (EMS) as well as in a standard clinical test (Test Battery for Attention Performance, TAP, Zimmermann \& Fimm, 1993). The aim of this study is to investigate whether cathodal stimulation leads to poorer test performance.

Detailed Description

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Conditions

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Visual Neglect

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Cathodal tDCS in young study participants

Cathodal tDCS in young study participants

Group Type EXPERIMENTAL

Cathodal tDCS

Intervention Type OTHER

Cathodal tDCS applied over the right PPC

Cathodal tDCS in elderly study participants

Cathodal tDCS in elderly study participants

Group Type EXPERIMENTAL

Cathodal tDCS

Intervention Type OTHER

Cathodal tDCS applied over the right PPC

Sham tDCS in young study participants

Sham tDCS in young study participants

Group Type SHAM_COMPARATOR

Sham tDCS

Intervention Type OTHER

Sham tDCS applied over the right PPC

Sham tDCS in elderly study participants

Sham tDCS in elderly study participants

Group Type SHAM_COMPARATOR

Sham tDCS

Intervention Type OTHER

Sham tDCS applied over the right PPC

Interventions

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Cathodal tDCS

Cathodal tDCS applied over the right PPC

Intervention Type OTHER

Sham tDCS

Sham tDCS applied over the right PPC

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Younger subjects

* aged between 18 and 35 years
* ability to provide written informed consent
* right-handedness
* Elderly subjects

* aged between 50 and 85 years
* ability to provide written informed consent
* right-handedness

Exclusion Criteria

* serious psychiatric disorders (including depression, psychosis) in the past
* severe neurological disorders (such as epilepsy, dementia, stroke) in the past
* current severe medical disorder
* drugs, medication or alcohol abuse at the time of the study
* severe traumatic brain injury or tumor in the past
* operations on the brain, trepanations
* metallic implants in the head / neck area (except in the mouth), such as screws, splinter, artificial cochlea, electrodes
* severe skin diseases (like eczema) or very sensitive skin in the head region in the past
* epilepsy in the family
* current use of neuroleptics, antiepileptics, antidepressants, L-dopa, benzo-diazepines
* current pregnancy or lactation
* current claustrophobia
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Median Klinik Berlin-Kladow

UNKNOWN

Sponsor Role collaborator

NeuroCure Clinical Research Center, Charite, Berlin

OTHER

Sponsor Role collaborator

Center for Stroke Research Berlin

OTHER

Sponsor Role collaborator

Free University of Berlin

OTHER

Sponsor Role collaborator

Humboldt-Universität zu Berlin

OTHER

Sponsor Role collaborator

Charite University, Berlin, Germany

OTHER

Sponsor Role lead

Responsible Party

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Andreas Meisel

Prof. Dr. med. Andreas Meisel

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Andreas Meisel, MD

Role: PRINCIPAL_INVESTIGATOR

Charite - Universitätsmedizin Berlin (NeuroCure Clinical Research Center)

Locations

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Charité University Medicine

Berlin, , Germany

Site Status

Countries

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Germany

Other Identifiers

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KMS-Neglect 2

Identifier Type: -

Identifier Source: org_study_id

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