Pelvic Floor Activity and Breathing in Women

NCT ID: NCT01694979

Last Updated: 2012-09-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

18 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-02-29

Study Completion Date

2012-02-29

Brief Summary

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The pelvic floor and diaphragm work together in many different functions. Two important functions are breathing and continence. The pelvic floor muscles have to lift and squeeze to maintain continence. Breathing, specifically breathing out, makes the pelvic floor lift. The investigators don't know how much the pelvic floor lifts and squeezes during different types of breathing out. The purpose of this study is to measure pelvic floor lift and squeeze during different types of breathing out.

Detailed Description

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The pelvic floor (PF) activates automatically, both squeezing and lifting, during times of increased intra-abdominal pressure for postural stability and continence. Expiration additionally produces automatic activation of the PF. No study to date has investigated the effects of forced expiration on PF displacement and squeeze pressure. The purpose of this study was to investigate the effects of variations in forced expiration effort on PF muscles' automatic activation.

Conditions

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Pelvic Floor Respiration

Keywords

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Pelvic floor Rehabilitation Respiration Urinary incontinence

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Single group: pelvic floor and breathing

This is a single group with repeated measures during variable breathing effort

Minimum expiration effort

Intervention Type OTHER

Subjects perform a forced expiration at minimum effort

Moderate expiration effort

Intervention Type OTHER

Subjects perform a forced expiration at moderate effort

Maximum expiration effort

Intervention Type OTHER

Subjects perform a forced expiration at maximum effort

Interventions

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Minimum expiration effort

Subjects perform a forced expiration at minimum effort

Intervention Type OTHER

Moderate expiration effort

Subjects perform a forced expiration at moderate effort

Intervention Type OTHER

Maximum expiration effort

Subjects perform a forced expiration at maximum effort

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* women
* young (age 18-35)
* nulliparous
* pre-menopausal

Exclusion Criteria

* pregnancy
* history of lower back or pelvic pain
* history of lower back or pelvic surgeries
* incontinence
* history of pelvic floor dysfunction
* diabetes
* endometriosis
* neuromuscular disease
* connective tissue disease
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Kitani, Lenore, PT

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Lenore J Kitani, B.S. PT

Role: PRINCIPAL_INVESTIGATOR

Texas Tech University Health Sciences Center

Locations

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Texas Tech University Health Sciences Center, Clinical Musculoskeletal Research Laboratory

Lubbock, Texas, United States

Site Status

Countries

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United States

References

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Hodges PW, Sapsford R, Pengel LH. Postural and respiratory functions of the pelvic floor muscles. Neurourol Urodyn. 2007;26(3):362-71. doi: 10.1002/nau.20232.

Reference Type BACKGROUND
PMID: 17304528 (View on PubMed)

Bo K, Berghmans B, Mørkved Siv, Van Kampen Marijke. Evidence-based physical therapy for the pelvic floor. 1st ed. Philedelphia, PA: Elsevier; 2007.

Reference Type BACKGROUND

Junginger B, Baessler K, Sapsford R, Hodges PW. Effect of abdominal and pelvic floor tasks on muscle activity, abdominal pressure and bladder neck. Int Urogynecol J. 2010 Jan;21(1):69-77. doi: 10.1007/s00192-009-0981-z.

Reference Type BACKGROUND
PMID: 19730763 (View on PubMed)

Thompson JA, O'Sullivan PB. Levator plate movement during voluntary pelvic floor muscle contraction in subjects with incontinence and prolapse: a cross-sectional study and review. Int Urogynecol J Pelvic Floor Dysfunct. 2003 Jun;14(2):84-8. doi: 10.1007/s00192-003-1036-5. Epub 2003 Apr 24.

Reference Type BACKGROUND
PMID: 12851748 (View on PubMed)

Talasz H, Kremser C, Kofler M, Kalchschmid E, Lechleitner M, Rudisch A. Phase-locked parallel movement of diaphragm and pelvic floor during breathing and coughing-a dynamic MRI investigation in healthy females. Int Urogynecol J. 2011 Jan;22(1):61-8. doi: 10.1007/s00192-010-1240-z. Epub 2010 Aug 31.

Reference Type BACKGROUND
PMID: 20809211 (View on PubMed)

Neumann P, Gill V. Pelvic floor and abdominal muscle interaction: EMG activity and intra-abdominal pressure. Int Urogynecol J Pelvic Floor Dysfunct. 2002;13(2):125-32. doi: 10.1007/s001920200027.

Reference Type BACKGROUND
PMID: 12054180 (View on PubMed)

Smith MD, Coppieters MW, Hodges PW. Postural activity of the pelvic floor muscles is delayed during rapid arm movements in women with stress urinary incontinence. Int Urogynecol J Pelvic Floor Dysfunct. 2007 Aug;18(8):901-11. doi: 10.1007/s00192-006-0259-7. Epub 2006 Dec 1.

Reference Type BACKGROUND
PMID: 17139463 (View on PubMed)

Ferreira CH, Barbosa PB, de Oliveira Souza F, Antonio FI, Franco MM, Bo K. Inter-rater reliability study of the modified Oxford Grading Scale and the Peritron manometer. Physiotherapy. 2011 Jun;97(2):132-8. doi: 10.1016/j.physio.2010.06.007. Epub 2010 Oct 22.

Reference Type BACKGROUND
PMID: 21497247 (View on PubMed)

Frawley HC, Galea MP, Phillips BA, Sherburn M, Bo K. Reliability of pelvic floor muscle strength assessment using different test positions and tools. Neurourol Urodyn. 2006;25(3):236-242. doi: 10.1002/nau.20201.

Reference Type BACKGROUND
PMID: 16299815 (View on PubMed)

Dietz HP. Pelvic floor ultrasound: a review. Am J Obstet Gynecol. 2010 Apr;202(4):321-34. doi: 10.1016/j.ajog.2009.08.018.

Reference Type BACKGROUND
PMID: 20350640 (View on PubMed)

Pregazzi R, Sartore A, Bortoli P, Grimaldi E, Troiano L, Guaschino S. Perineal ultrasound evaluation of urethral angle and bladder neck mobility in women with stress urinary incontinence. BJOG. 2002 Jul;109(7):821-7. doi: 10.1111/j.1471-0528.2002.01163.x.

Reference Type BACKGROUND
PMID: 12135220 (View on PubMed)

Peschers UM, Gingelmaier A, Jundt K, Leib B, Dimpfl T. Evaluation of pelvic floor muscle strength using four different techniques. Int Urogynecol J Pelvic Floor Dysfunct. 2001;12(1):27-30. doi: 10.1007/s001920170090.

Reference Type BACKGROUND
PMID: 11294527 (View on PubMed)

Thompson JA, O'Sullivan PB, Briffa K, Neumann P, Court S. Assessment of pelvic floor movement using transabdominal and transperineal ultrasound. Int Urogynecol J Pelvic Floor Dysfunct. 2005 Jul-Aug;16(4):285-92. doi: 10.1007/s00192-005-1308-3. Epub 2005 Mar 22.

Reference Type BACKGROUND
PMID: 15782286 (View on PubMed)

Shishido K, Peng Q, Jones R, Omata S, Constantinou CE. Influence of pelvic floor muscle contraction on the profile of vaginal closure pressure in continent and stress urinary incontinent women. J Urol. 2008 May;179(5):1917-22. doi: 10.1016/j.juro.2008.01.020. Epub 2008 Mar 18.

Reference Type BACKGROUND
PMID: 18353401 (View on PubMed)

Bo K, Finckenhagen HB. Is there any difference in measurement of pelvic floor muscle strength in supine and standing position? Acta Obstet Gynecol Scand. 2003 Dec;82(12):1120-4. doi: 10.1046/j.1600-0412.2003.00240.x.

Reference Type BACKGROUND
PMID: 14616257 (View on PubMed)

Constantinou CE, Hvistendahl G, Ryhammer A, Nagel LL, Djurhuus JC. Determining the displacement of the pelvic floor and pelvic organs during voluntary contractions using magnetic resonance imaging in younger and older women. BJU Int. 2002 Sep;90(4):408-14. doi: 10.1046/j.1464-410x.2002.02907.x.

Reference Type BACKGROUND
PMID: 12175398 (View on PubMed)

Schaer GN, Koechli OR, Schuessler B, Haller U. Perineal ultrasound for evaluating the bladder neck in urinary stress incontinence. Obstet Gynecol. 1995 Feb;85(2):220-4. doi: 10.1016/0029-7844(94)00369-O.

Reference Type BACKGROUND
PMID: 7824234 (View on PubMed)

Sapsford R. Rehabilitation of pelvic floor muscles utilizing trunk stabilization. Man Ther. 2004 Feb;9(1):3-12. doi: 10.1016/s1356-689x(03)00131-0.

Reference Type BACKGROUND
PMID: 14723856 (View on PubMed)

Avery K, Donovan J, Peters TJ, Shaw C, Gotoh M, Abrams P. ICIQ: a brief and robust measure for evaluating the symptoms and impact of urinary incontinence. Neurourol Urodyn. 2004;23(4):322-30. doi: 10.1002/nau.20041.

Reference Type BACKGROUND
PMID: 15227649 (View on PubMed)

Morin M, Bourbonnais D, Gravel D, Dumoulin C, Lemieux MC. Pelvic floor muscle function in continent and stress urinary incontinent women using dynamometric measurements. Neurourol Urodyn. 2004;23(7):668-74. doi: 10.1002/nau.20069.

Reference Type BACKGROUND
PMID: 15382183 (View on PubMed)

Teleman PM, Gunnarsson M, Lidfeldt J, Nerbrand C, Samsioe G, Mattiasson A. Urethral pressure changes in response to squeeze: a population-based study in healthy and incontinent 53- to 63-year-old women. Am J Obstet Gynecol. 2003 Oct;189(4):1100-5. doi: 10.1067/s0002-9378(03)00539-8.

Reference Type BACKGROUND
PMID: 14586362 (View on PubMed)

Bo K, Kvarstein B, Hagen RR, Larsen S. Pelvic floor muscle exercise for the treatment of female stress urinary incontinence: II. Validity of vaginal pressure measurements of pelvic floor muscle strength and the necessity of supplementary methods for control of correct contraction. Neurourol Urodyn 1990;9(5):479-487.

Reference Type BACKGROUND

Bo K, Constantinou C. Reflex contraction of pelvic floor muscles during cough cannot be measured with vaginal pressure devices. Neurourol Urodyn. 2011 Sep;30(7):1404. doi: 10.1002/nau.20993. Epub 2011 Mar 14. No abstract available.

Reference Type BACKGROUND
PMID: 21404321 (View on PubMed)

Sherburn M, Bird M, Carey M, Bo K, Galea MP. Incontinence improves in older women after intensive pelvic floor muscle training: an assessor-blinded randomized controlled trial. Neurourol Urodyn. 2011 Mar;30(3):317-24. doi: 10.1002/nau.20968. Epub 2011 Jan 31.

Reference Type BACKGROUND
PMID: 21284022 (View on PubMed)

Hung HC, Hsiao SM, Chih SY, Lin HH, Tsauo JY. An alternative intervention for urinary incontinence: retraining diaphragmatic, deep abdominal and pelvic floor muscle coordinated function. Man Ther. 2010 Jun;15(3):273-9. doi: 10.1016/j.math.2010.01.008. Epub 2010 Feb 24.

Reference Type BACKGROUND
PMID: 20185357 (View on PubMed)

Dinc A, Kizilkaya Beji N, Yalcin O. Effect of pelvic floor muscle exercises in the treatment of urinary incontinence during pregnancy and the postpartum period. Int Urogynecol J Pelvic Floor Dysfunct. 2009 Oct;20(10):1223-31. doi: 10.1007/s00192-009-0929-3. Epub 2009 Aug 1.

Reference Type BACKGROUND
PMID: 19649552 (View on PubMed)

Miller JM, Perucchini D, Carchidi LT, DeLancey JO, Ashton-Miller J. Pelvic floor muscle contraction during a cough and decreased vesical neck mobility. Obstet Gynecol. 2001 Feb;97(2):255-60. doi: 10.1016/s0029-7844(00)01132-7.

Reference Type BACKGROUND
PMID: 11165591 (View on PubMed)

Barbic M, Kralj B, Cor A. Compliance of the bladder neck supporting structures: importance of activity pattern of levator ani muscle and content of elastic fibers of endopelvic fascia. Neurourol Urodyn. 2003;22(4):269-76. doi: 10.1002/nau.10116.

Reference Type BACKGROUND
PMID: 12808700 (View on PubMed)

Other Identifiers

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L12-020

Identifier Type: -

Identifier Source: org_study_id