Prospective, Multicenter Trial to Investigate the Safety and Efficacy of Percutaneous Tibial Nerve Stimulation for the Treatment of Fecal Incontinence

NCT ID: NCT01666405

Last Updated: 2015-10-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

PHASE1

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-08-31

Study Completion Date

2015-04-30

Brief Summary

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The purpose of this study is to determine the effectiveness of percutaneous tibial nerve stimulation (PTNS) therapy with the Urgent® PC Neuromodulation System (Uroplasty, Inc., Minnetonka, MN, USA) for the treatment of fecal incontinence (FI).

Detailed Description

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Pilot Study

Conditions

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Fecal Incontinence

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Urgent(R) PC Neuromodulation System

Urgent(R) PC Neuromodulation System

Group Type EXPERIMENTAL

Urgent(R) PC Neuromodulation System

Intervention Type DEVICE

The Urgent PC Neuromodulation System (Uroplasty, Inc., Minnetonka, MN, USA), device, is an easily administered neuromodulation system designed to deliver retrograde access to the sacral nerve through percutaneous electrical stimulation of the tibial nerve. This method of treatment is referred to as percutaneous tibial nerve stimulation (PTNS).

Interventions

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Urgent(R) PC Neuromodulation System

The Urgent PC Neuromodulation System (Uroplasty, Inc., Minnetonka, MN, USA), device, is an easily administered neuromodulation system designed to deliver retrograde access to the sacral nerve through percutaneous electrical stimulation of the tibial nerve. This method of treatment is referred to as percutaneous tibial nerve stimulation (PTNS).

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patient history of chronic FI of more than staining for at least 6 months; staining defined as less than the size of a 25¢ piece (quarter)
* Patient reported and/or failed ≥ 2 conservative therapies (e.g., diet/fiber modification, anti-diarrheal medication, pelvic floor muscle training, biofeedback, medical management, etc.)

Exclusion Criteria

* Pregnancy or intention to become pregnant during the course of the study
* Implanted electro-medical device (i.e., pacemaker, defibrillator, deep brain stimulator, etc.)
* Clinically significant neurological diseases or nerve damage impacting tibial nerve or pelvic floor function
* Prone to excessive bleeding or bleeding diathesis
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Uroplasty, Inc

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Kaiser Permanente Los Angeles Medical Center

Los Angeles, California, United States

Site Status

UCSF Center for Colorectal Surgery

San Francisco, California, United States

Site Status

Minnesota Colon and Rectal Surgery Associates, Ltd.

Minneapolis, Minnesota, United States

Site Status

The Lindner Center for Research and Education at The Christ Hospital

Cincinnati, Ohio, United States

Site Status

Colorectal Surgical Asociates

Houston, Texas, United States

Site Status

Providence Health and Services

Spokane, Washington, United States

Site Status

Countries

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United States

Other Identifiers

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UPC032012

Identifier Type: -

Identifier Source: org_study_id

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