Study of NMB Drug Ejecting Balloon for Peripheral Arteries

NCT ID: NCT01646801

Last Updated: 2012-07-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-01-31

Study Completion Date

2015-01-31

Brief Summary

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The purpose of this study is to demonstrate the Safety and effectiveness of the use of NMB's drug ejecting balloon for the treatment of de novo and restenotic lesions in peripheral arterial disease.

Detailed Description

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Conditions

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Peripheral Arterial Disease

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Experimental

NMB's Paclitaxel Drug ejecting balloon catheter

Group Type EXPERIMENTAL

NMB Balloon Catheter

Intervention Type DEVICE

patients treated by the NMB's Drug Ejecting Balloon

Interventions

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NMB Balloon Catheter

patients treated by the NMB's Drug Ejecting Balloon

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients 18 years old or older
* Patient with lifestyle limiting claudication or rest pain (Rutherford- Becker scale 2, 3 or 4).
* Patient with de novo lesion or restenotic lesion ≥70% in the iliac, femoral, popliteal or tibial artery.
* The target lesion can be successfully crossed with a guide wire and dilated.
* The target lesion is in a native artery of 2.5-10mm in diameter and less than 80 mm in length.
* Patient is willing to and able to sign a written informed consent and to comply with procedures (e.g., adherence to follow-up visits, including 6 months CT-angiography/MRA follow-up).

Exclusion Criteria

* Women who are pregnant or breast-feeding and women of childbearing potential who do not use adequate contraception.
* Previous participation in another study with any investigational drug or device within the past 30 days.
* The patient is currently enrolled in another investigational device or drug trial.
* Severe reaction to contrast agents that cannot be adequately premedicated prior to procedure.
* Stenosis with corresponding thrombosis treated within 7 days before enrollment.
* Patient with known contraindications for aspirin or other anticoagulant/antiplatelet therapy.
* Patient that has co-morbid illness that may result in life expectancy of less than 12 months.
* History of haemorrhagic stroke or gastro-intestinal bleeding within 6 months.
* Patient with major surgery during the 30 days preceding the interventional procedure.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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N.M.B. Medical Applications Ltd

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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The Rabin Medical Center, Hasharon Hospital

Petah Tikva, , Israel

Site Status

Countries

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Israel

Central Contacts

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Eli Atar, MD

Role: CONTACT

Phone: 972-3-9376389

Email: [email protected]

Other Identifiers

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NMB PP CLD 2158

Identifier Type: -

Identifier Source: org_study_id