Pneumatic Retinopexy Versus Vitrectomy for Retinal Detachment

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

176 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-08-31

Study Completion Date

2017-05-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this research study is to compare the outcomes of pneumatic retinopexy with the outcomes of vitrectomy (with or without scleral buckle) for the management of retinal detachment, in terms of anatomical success, functional success and impact on patient quality of life.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Pneumatic Retinopexy Versus Vitrectomy for Retinal Detachment in Patients With Extended Criteria

NCT02871531

Rhegmatogenous Retinal Detachment

UNKNOWN NA

Pneumatic Retinopexy for Primary Rhegmatogenous Retinal Detachment: To Steamroll or Not

NCT04723420

Rhegmatogenous Retinal Detachment

UNKNOWN NA

Retinal Displacement After Pneumatic Versus Vitrectomy for Retinal Detachment (ALIGN)

NCT04089033

Retinal Detachment Metamorphopsia Aniseikonia

COMPLETED

Retinal Displacement Rates in Pneumatic Retinopexy Versus Pars Plana Vitrectomy For Primary Retinal Detachment

NCT04158622

Retinal Detachment Metamorphopsia

UNKNOWN NA

Pneumatic Retinopexy Versus Vitrectomy With Gas for Retinal Detachment Due to Myopic Macular Hole

NCT00485199

Retinal Detachment

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Rhegmatogenous retinal detachment (RRD)is an acute, sight threatening condition, with an incidence of approximately 10 per 100,000 population. Both of the treatments under investigation are widely used and accepted by vitreoretinal surgeons, but randomised, prospective comparison of the two techniques has not been reported in the scientific literature to date. Currently, the management decisions surrounding primary retinal detachment are grounded on a weak evidence base. The findings of this study will allow vitreoretinal surgeons and their patients to select the most appropriate intervention for that individual, in an informed and holistic manner.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Rhegmatogenous Retinal Detachment

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Vitrectomy

Group Type EXPERIMENTAL

Vitrectomy

Intervention Type PROCEDURE

Pars plana vitrectomy plus laser/cryotherapy

Pneumatic retinopexy

Group Type EXPERIMENTAL

Pneumatic retinopexy

Intervention Type PROCEDURE

Pneumatic retinopexy plus laser/cryotherapy

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Vitrectomy

Pars plana vitrectomy plus laser/cryotherapy

Intervention Type PROCEDURE

Pneumatic retinopexy

Pneumatic retinopexy plus laser/cryotherapy

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients presenting with acute rhegmatogenous retinal detachment
* Single retinal break OR group of breaks no larger than one clock hour (30°)
* All break/s in detached retina between 8-4 o'clock
* No significant proliferative vitreoretinopathy

Exclusion Criteria

* Inferior breaks in detached retina
* Inability to read English language
* Age \< 18 years
* Mental incapacity
* Previous vitrectomy (index eye)
* Previous retinal detachment (index eye)
* Inability to maintain the post-operative posturing
* Inability to carry out detailed examination of peripheral retina due to media opacity

Eligible Sex

ALL

Accepts Healthy Volunteers

No