NT-proBNP as a Tool for the Detection of Acute Pulmonary Artery Embolism (APE)

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

44 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-11-30

Study Completion Date

2011-12-31

Brief Summary

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In patients with suspected APE (Acute Pulmonary Embolism) referred to the intensive care unit (ICU)after major surgery, serum NT-proBNP (N-terminal proBNP), Troponin-I and D-dimers were measured according to the standard hospital protocol. To definitively confirm or exclude APE, all patients underwent an angiographic CT-scan of the thorax.

Detailed Description

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In patients with suspected APE referred to the intensive care unit after major surgery, serum NT-proBNP, Troponin-I and D-dimers were measured according to the standard hospital protocol. Blood samples were obtained within one hour after the onset of clinical symptoms.

Definitive confirmation or exclusion of APE was performed with an angiographic CT-scan of the thorax.

Conditions

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Pulmonary Embolism Pulmonary Embolism Without Mention of Acute Cor Pulmonale

Keywords

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Misadventures to Patients During Surgical and Medical Care Pulmonary Embolism Without Acute Cor Pulmonale Pulmonary Embolism Without Mention of Acute Cor Pulmonale

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Suspected APE

Post-surgical patients with clinically suspected acute pulmonary embolism

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

all patients referred to the ICU with suspected APE

Exclusion Criteria

none

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Claus-Martin Muth

Claus-Martin Muth, MD, PhD - Head of the Department of Emergency Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Claus M Muth, MD

Role: STUDY_CHAIR

Dept. of Anesthesiology, Div. of Emergency medicine, University hospital Ulm, 89075 Ulm, Germany

Bernd E Winkler, MD

Role: PRINCIPAL_INVESTIGATOR

Dept. of Anesthesiology, University hospital Ulm, 89075 Ulm, Germany

Locations

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University of Ulm, Michelsberg anaesthesiologic ICU

Ulm, Baden-Wurttemberg, Germany

Site Status

Countries

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Germany

Other Identifiers

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ana-ulm-ntprobnp-288/11

Identifier Type: -

Identifier Source: org_study_id