Subclinical Delirium and Clinical Outcome

NCT ID: NCT01616914

Last Updated: 2013-04-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

250 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-01-31

Study Completion Date

2012-08-31

Brief Summary

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Delirium has been associated with clinical outcomes in critical care setting. However, its subclinical form has not been investigated. The investigators aimed to establish the association of subclinical delirium with outcome.

Detailed Description

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Delirium has been associated with clinical outcome in critical care setting. This syndrome has been associated with longer length of stay in ICU and hospital, longer duration of mechanical ventilation and higher mortality rate. however, its subclinical form has not been investigated. The subclinical syndrome is defined by CAM-ICU, in which several features of delirium are fulfilled but the diagnostic criteria are not fulfilled. The investigators aimed to establish the association of subclinical delirium with outcome.

Conditions

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Delirium

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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delirium group

patients with delirium during ICU stay

No interventions assigned to this group

non-delirium group

patients without delirium during ICU stay

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* patients enter ICU
* GCS \> 10
* RASS \> -2

Exclusion Criteria

* unable to cooperate
* coma
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Jinhua Central Hospital

OTHER

Sponsor Role lead

Responsible Party

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Zhongheng Zhang

Jinhua central hospital

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Zhongheng Zhang, MM

Role: STUDY_CHAIR

Jinhua Central Hospital

Locations

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Jinhua central hospital

Jinhua, Zhejiang, China

Site Status

Countries

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China

References

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van den Boogaard M, Pickkers P, Slooter AJ, Kuiper MA, Spronk PE, van der Voort PH, van der Hoeven JG, Donders R, van Achterberg T, Schoonhoven L. Development and validation of PRE-DELIRIC (PREdiction of DELIRium in ICu patients) delirium prediction model for intensive care patients: observational multicentre study. BMJ. 2012 Feb 9;344:e420. doi: 10.1136/bmj.e420.

Reference Type BACKGROUND
PMID: 22323509 (View on PubMed)

van den Boogaard M, Schoonhoven L, van der Hoeven JG, van Achterberg T, Pickkers P. Incidence and short-term consequences of delirium in critically ill patients: A prospective observational cohort study. Int J Nurs Stud. 2012 Jul;49(7):775-83. doi: 10.1016/j.ijnurstu.2011.11.016. Epub 2011 Dec 22.

Reference Type BACKGROUND
PMID: 22197051 (View on PubMed)

Tomasi CD, Grandi C, Salluh J, Soares M, Giombelli VR, Cascaes S, Macedo RC, de Souza Constantino L, Biff D, Ritter C, Dal Pizzol F. Comparison of CAM-ICU and ICDSC for the detection of delirium in critically ill patients focusing on relevant clinical outcomes. J Crit Care. 2012 Apr;27(2):212-7. doi: 10.1016/j.jcrc.2011.05.015. Epub 2011 Jul 6.

Reference Type BACKGROUND
PMID: 21737237 (View on PubMed)

Other Identifiers

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ZZH-2

Identifier Type: -

Identifier Source: org_study_id

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