Instruments for Delirium Assessment Regarding to Analgesia Sedation and Ventilator Status

NCT ID: NCT01720914

Last Updated: 2015-12-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

160 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-11-30

Study Completion Date

2015-12-31

Brief Summary

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In this prospective, multicenter observational study we assess the diagnostic validity of the following standard screening instruments for delirium regarding sedation, analgesia and ventilator status in critically ill patients:

* Confusion Assessment Method for the ICU (CAM-ICU)
* Intensive Care Delirium Screening Checklist (ICDSC)
* Nursing-Delirium-Screening-Scale (Nu-DESC)

The definite delirium diagnosis (definite in terms of reference standard) is made according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders 4th Edition, text revised (DSM-IV-TR) published by the American Psychiatric Association (APA) which is the Gold Standard to diagnose delirium.

Primary research question: Does sedation, ventilator status and analgesia influence the sensitivity of delirium screening tools (DST)?

Detailed Description

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Conditions

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Delirium

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Critically ill patient

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Critically ill patient
* Patient age \> 18 years

Exclusion Criteria

* Neurosurgical patients
* Severe brain injury, intracerebral bleeding, stroke
* Inability to communicate due to anacusia or severe hearing loss
* Insufficient language comprehension
* Patients \< 24 h total time of Intensive Care Unit stay
* Deep sedation (RASS \< -3) for ≥ 7 days during study participation
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Charite University, Berlin, Germany

OTHER

Sponsor Role lead

Responsible Party

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Claudia Spies

Department of Anesthesiology and Intensive Care Medicine CVK/CCM, Charite University, Berlin, Germany

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Centro de Terapia Intensiva da Hospital Pro-Cardiaco

Botafogo, Rio de Janeiro, Brazil

Site Status

Department of Anesthesiology and Intensive Care Medicine, CVK/CCM, Charité -University Medicine

Berlin, State of Berlin, Germany

Site Status

Countries

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Brazil Germany

References

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Nacul FE, Paul N, Spies CD, Sechting H, Hecht T, Dullinger JS, Piper SK, Luetz A, Balzer FS, Wernecke KD, Sa AK, Barros Ferreira da Costa C, Eymold L, Chenitir C, Weiss B. Influence of Sedation Level and Ventilation Status on the Diagnostic Validity of Delirium Screening Tools in the ICU-An International, Prospective, Bi-Center Observational Study (IDeAS). Medicina (Kaunas). 2020 Aug 13;56(8):411. doi: 10.3390/medicina56080411.

Reference Type DERIVED
PMID: 32823781 (View on PubMed)

Other Identifiers

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IDEAS

Identifier Type: -

Identifier Source: org_study_id