The Microcirculation in Acute Myocardial Infarction (Micro-AMI)
NCT ID: NCT01552564
Last Updated: 2014-10-28
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
50 participants
OBSERVATIONAL
2012-03-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_ONLY
PROSPECTIVE
Study Groups
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STEMI patients
Consecutive patients presenting through the PPCI service
Index of microvascular resistance
Cardiac magnetic resonance
Blood markers
Interventions
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Index of microvascular resistance
Cardiac magnetic resonance
Blood markers
Eligibility Criteria
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Inclusion Criteria
* Cardiac symptoms of \> 20 mins chest pain or equivalent.
* ECG criteria consistent with STEMI (STEMI)
* Proceeding with percutaneous angioplasty
* Assent/ consent to the study
Exclusion Criteria
* Chronic atrial fibrillation
* Renal impairment with eGFR \<30
* Contraindication to angiography
* Contraindication to CMR (implanted pacemaker/ defibrillator, ferromagnetic metal implant/ injury, claustrophobia, obesity/ too large for CMR scanner)
* Cardiogenic shock
* Patients with special communication needs or altered consciousness.
* Patients who do not give assent/consent to the study
18 Years
ALL
No
Sponsors
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University of Bristol
OTHER
Responsible Party
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Elisa McAlindon
Clinical Research Fellow
Locations
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Bristol Heart Institute
Bristol, , United Kingdom
Countries
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References
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McAlindon E, Pufulete M, Harris J, Lawton C, Johnson T, Strange J, Baumbach A, Bucciarelli-Ducci C. Microvascular dysfunction determines infarct characteristics in patients with reperfused ST-segment elevation myocardial infarction: The MICROcirculation in Acute Myocardial Infarction (MICRO-AMI) study. PLoS One. 2018 Nov 13;13(11):e0203750. doi: 10.1371/journal.pone.0203750. eCollection 2018.
Other Identifiers
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1625
Identifier Type: -
Identifier Source: org_study_id
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