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Myocardial Work for Prediction of Left Ventricular Remodeling in Patients With STEMI

NCT ID: NCT05107102

Last Updated: 2021-11-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

98 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-09-10

Study Completion Date

2021-08-30

Brief Summary

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The study intends to investigate the alteration of regional myocardial work in patients with acute anterior myocardial infarction underwent primary percutaneous coronary intervention (PCI), and compare the distribution of regional myocardial work in patients with/without early remodeling at acute phase and 3-month follow-up.

Detailed Description

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Conditions

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ST-Segment Elevated Myocardial Infarction

Keywords

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ST-segment elevated myocardial infarction myocardial work left ventricular remodeling

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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patients with LVR(left ventricular remodeling)

No interventions assigned to this group

patients without LVR(left ventricular remodeling)

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Anterior myocardial infarct (anterior myocardial infarct is defined as persistent chest pain for 30 mins at least, with ST-segment elevation of at least 0.2 mV in two or more contiguous precordial leads) within 12 hours after onsets of symptom;
* Left anterior descending (LAD) as culprit vessel, with TIMI 0-1 grade.

Exclusion Criteria

* significant valvular disease;
* cardiomyopathy; l
* left bundle branch block;
* atrial fibrillation;
* previous myocardial infarction (MI);
* history of cardiac surgery;
* pacemaker implantation.
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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RenJi Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Song Ding, MD,PHD

Role: PRINCIPAL_INVESTIGATOR

Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University

Locations

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Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University

Shanghai, Shanghai Municipality, China

Site Status

Countries

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China

References

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Wang W, Zhao H, Wan F, Shen XD, Ding S, Pu J. Inhomogeneous Distribution of Regional Myocardial Work Efficiency Predicts Early Left Ventricular Remodeling After Acute Anterior Myocardial Infarction Treated With Primary Percutaneous Intervention. Front Cardiovasc Med. 2022 Jul 27;9:922567. doi: 10.3389/fcvm.2022.922567. eCollection 2022.

Reference Type DERIVED
PMID: 35966524 (View on PubMed)

Other Identifiers

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STEMI-myocardial work

Identifier Type: -

Identifier Source: org_study_id