Interferential Electrical Stimulation and Vasodilatation in Healthy Individuals

NCT ID: NCT01450371

Last Updated: 2013-01-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

11 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-07-31

Study Completion Date

2012-10-31

Brief Summary

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Interferential electrical stimulation (IES) increases local blood flow. It is not known whether increases in blood flow may be caused by inhibition of sympathetic activity, mediated by muscle metaboreflex activity. The purpose of this study was to evaluate the effect of IES on metaboreflex activation in healthy subjects.

Detailed Description

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The study sample consisted of 11 healthy young individuals. All subjects were non-smokers, non-obese and free of any signs or symptoms of disease, as revealed by medical history, physical examination and electrocardiogram at rest and during cardiopulmonary exercise testing. Exclusion criteria were pregnancy, breast-feeding, alcohol or drug abuse, and any medication with potential effects on cardiovascular variables. Subjects were asked not to drink caffeine-containing drinks or exercise for at least 12 and 48 hours, respectively, before the experimental protocols.

Conditions

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Decreased Vascular Flow

Study Design

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Study Time Perspective

PROSPECTIVE

Study Groups

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Interferential

The individuals are treated acutely with interferential electrical stimulation (IES) during 30 min, providing a continuous flow of symmetrical rectangular interferential current biphasic pulses using bipolar electrodes with two channels and a slope of 1/5/1. The fixed current is adjusted to 4000 Hz, with the current AMF at 100 Hz and an AMF variation of 25 Hz (25% of AMF).

Interferential

Intervention Type DEVICE

The individuals are treated acutely with IES during 30 min, providing a continuous flow of symmetrical rectangular interferential current biphasic pulses using bipolar electrodes with two channels and a slope of 1/5/1. The fixed current is adjusted to 4000 Hz, with the current AMF at 100 Hz and an AMF variation of 25 Hz (25% of AMF).

Placebo

The same instructions and electrode positions were provided to the placebo, although the equipment did not provide any stimulation current

Interferential Placebo

Intervention Type DEVICE

The same instructions and electrode positions were provided to the placebo, although the equipment did not provide any stimulation current

Interventions

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Interferential

The individuals are treated acutely with IES during 30 min, providing a continuous flow of symmetrical rectangular interferential current biphasic pulses using bipolar electrodes with two channels and a slope of 1/5/1. The fixed current is adjusted to 4000 Hz, with the current AMF at 100 Hz and an AMF variation of 25 Hz (25% of AMF).

Intervention Type DEVICE

Interferential Placebo

The same instructions and electrode positions were provided to the placebo, although the equipment did not provide any stimulation current

Intervention Type DEVICE

Other Intervention Names

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Transcutaenous electrical stimuation

Eligibility Criteria

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Inclusion Criteria

* Subjects are non-smokers
* non-obese
* and free of any signs or symptoms of disease

Exclusion Criteria

* Pregnancy
* breast-feeding
* alcohol or drug abuse
* medication with potential effects on cardiovascular variables
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Brasilia

OTHER

Sponsor Role collaborator

Hospital de Clinicas de Porto Alegre

OTHER

Sponsor Role lead

Responsible Party

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GASPAR ROGERIO DA SILVA CHIAPPA, Principal Investigator

Gaspar Rogério da Silva Chiappa

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Gaspar R Chiappa, Dr

Role: PRINCIPAL_INVESTIGATOR

Hospital de Clinicas de Porto Alegre

Locations

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University of Brasilia

Brasília, Federal District, Brazil

Site Status

Hospital de Clinicas de Porto Alegre

Porto Alegre, Rio Grande do Sul, Brazil

Site Status

Gaspar Rogério da Silva Chiappa

Porto Alegre, Rio Grande do Sul, Brazil

Site Status

Countries

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Brazil

References

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Vieira PJ, Ribeiro JP, Cipriano G Jr, Umpierre D, Cahalin LP, Moraes RS, Chiappa GR. Effect of transcutaneous electrical nerve stimulation on muscle metaboreflex in healthy young and older subjects. Eur J Appl Physiol. 2012 Apr;112(4):1327-34. doi: 10.1007/s00421-011-2084-z. Epub 2011 Jul 28.

Reference Type BACKGROUND
PMID: 21796410 (View on PubMed)

Other Identifiers

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11-0374

Identifier Type: -

Identifier Source: org_study_id

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