Physical Activity for a Long and Healthy Life

NCT ID: NCT01430143

Last Updated: 2018-08-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

64 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-09-30

Study Completion Date

2011-06-30

Brief Summary

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The aim of the study is to 1) delineate the molecular mechanisms behind the large variation in insulin sensitivity among apparently healthy subjects and to 2) establish the dose-response relationship between physical training and a) metabolic health, b) appetite and c) cultural health.

Detailed Description

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Conditions

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Overweight Insulin Resistance Diabetes Mellitus, Type 2

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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600 kcal/day

Exercise combusting 600 kcal/day, 7 days/week for 12 weeks.

Group Type EXPERIMENTAL

Exercise

Intervention Type BEHAVIORAL

Daily exercise for 12 weeks.

300 kcal/day

Exercise combusting 300 kcal/day, 7 days/week for 12 weeks.

Group Type EXPERIMENTAL

Exercise

Intervention Type BEHAVIORAL

Daily exercise for 12 weeks.

Sedentary

Continued sedentary living.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Exercise

Daily exercise for 12 weeks.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Healthy according to interview
* Caucasian
* Sedentary, Vo2max \< 45 ml/kg/min
* BMI 25-30 kg/m2
* Fat percentage 25% \<
* Weight stable (+/- 2 kg within past 6 months)

Exclusion Criteria

* First degree relatives with type 2 diabetes
* Hemoglobin concentration \< 8 mmol/l
* Fasting plasma glucose 6.1 mmol/l \<
* Blood pressure 140/90 mmHg \<
* Regular intake of medicine
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Universitetssenteret på Kjeller

OTHER

Sponsor Role collaborator

Center for Healthy Aging

UNKNOWN

Sponsor Role collaborator

The Novo Nordic Foundation

OTHER

Sponsor Role collaborator

Copenhagen University Hospital, Denmark

OTHER

Sponsor Role collaborator

Glostrup University Hospital, Copenhagen

OTHER

Sponsor Role collaborator

University of Copenhagen

OTHER

Sponsor Role lead

Responsible Party

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Bente Merete Stallknecht

Associate professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Department of Biomedical Sciences, The University of Copenhagen

Copenhagen, , Denmark

Site Status

Countries

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Denmark

Related Links

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http://fine.ku.dk

Click here for more information about this study: Physical Activity for a Long and Healthy Life

Other Identifiers

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FourINonE

Identifier Type: -

Identifier Source: org_study_id

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