Effect of Intervention With Diet and Physical Activity in Obese Pregnant Women

NCT ID: NCT01345149

Last Updated: 2012-09-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

420 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-04-30

Study Completion Date

2012-06-30

Brief Summary

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Purpose: To evaluate if lifestyle intervention (diet and exercise) can reduce maternal weight gain, the incidence of pregnancy complications and minimize the number of macrosomic infants.

Detailed Description

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Obese pregnant women with a BMI\>30 are randomized to Diet + Exercise, Exercise or control (1:1:1) in order to reduce maternal weight gain to less than 5 kg during pregnancy.

The effect on the children of mothers in this study is evaluated in the study: Is it possible to reduce the Number of Macrosomic Infants With Abundant Fat Tissue by Lifestyle Intervention during Pregnancy (NCT01235676)

Conditions

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Obesity

Keywords

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Obesity Pregnancy Intervention Diet Physical activity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Diet + Exercise

Diet: Intensive counselling about calorie restriction to reduce weight gain by dietician.

Exercise: Individual counselling

Group Type EXPERIMENTAL

Diet + Exercise

Intervention Type BEHAVIORAL

Diet: Intensive counselling about calorie restriction to reduce weight gain by dietician.

Exercise: Individual counselling

Exercise

Exercise: Individual counselling

Group Type EXPERIMENTAL

Diet + Exercise

Intervention Type BEHAVIORAL

Diet: Intensive counselling about calorie restriction to reduce weight gain by dietician.

Exercise: Individual counselling

Control

Standard treatment without intervention.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Diet + Exercise

Diet: Intensive counselling about calorie restriction to reduce weight gain by dietician.

Exercise: Individual counselling

Intervention Type BEHAVIORAL

Other Intervention Names

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Lifestyle intervention.

Eligibility Criteria

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Inclusion Criteria

* Age \>18 years
* BMI \> 30
* Singleton pregnancy
* Must speak and understand Danish

Exclusion Criteria

* Alcohol or drug abuse
* Diabetes type I or other critical medical disease.
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Hvidovre University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Kristina Renault

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Niels Jørgen Secher, Professor

Role: STUDY_CHAIR

Department of Obstetrics and Gynecology, Hvidovre University Hospital

Lisbeth Nilas, Prof. DMSc

Role: STUDY_CHAIR

Department of Obstetrics and Gynecology, Hvidovre University Hospital

Locations

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Department of Obstetrics and Gynecology, Hvidovre University Hospital

Copenhagen, , Denmark

Site Status

Countries

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Denmark

References

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Renault KM, Carlsen EM, Norgaard K, Nilas L, Pryds O, Secher NJ, Cortes D, Jensen JE, Olsen SF, Halldorsson TI. Intake of carbohydrates during pregnancy in obese women is associated with fat mass in the newborn offspring. Am J Clin Nutr. 2015 Dec;102(6):1475-81. doi: 10.3945/ajcn.115.110551. Epub 2015 Nov 11.

Reference Type DERIVED
PMID: 26561621 (View on PubMed)

Renault KM, Carlsen EM, Norgaard K, Nilas L, Pryds O, Secher NJ, Olsen SF, Halldorsson TI. Intake of Sweets, Snacks and Soft Drinks Predicts Weight Gain in Obese Pregnant Women: Detailed Analysis of the Results of a Randomised Controlled Trial. PLoS One. 2015 Jul 20;10(7):e0133041. doi: 10.1371/journal.pone.0133041. eCollection 2015.

Reference Type DERIVED
PMID: 26192183 (View on PubMed)

Other Identifiers

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H-D-2008-119

Identifier Type: -

Identifier Source: org_study_id