The Effect of Prophylactic Hemodialysis on the Morbidity and Mortality of the Patients With Chronic Kidney Disease Stages 3-4 Undergoing Coronary Artery Graft Bypass

NCT ID: NCT01410617

Last Updated: 2013-03-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE2/PHASE3

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-08-31

Study Completion Date

2013-12-31

Brief Summary

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Coronary artery disease is a major cause of death in patients with renal dysfunction Among patients who undergo coronary artery bypass grafting ,renal dysfunction is known To be a major predictor of in-hospital and remote mortality As little is known about the impact of non-dialysis-dependent renal dysfunction on short and mid term Outcomes following coronary surgery we have decided to investigate the effect of prophylactic Hemodialysis on the mortality and morbidity of the patients with ckd (stage 3,4 ) and compare these Effect with the control group

Detailed Description

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Conditions

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Chronic Kidney Disease stage3 Chronic Kidney Disease stage4 Coronary Artery Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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dialysis

the patients who undergo 3 sessions prophylactic hemodialysis

Group Type ACTIVE_COMPARATOR

hemodialysis

Intervention Type PROCEDURE

3 sessions hemodialysis before CABG

control group

the patients who do not undergo hemodialysis

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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hemodialysis

3 sessions hemodialysis before CABG

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* 80\<age\>18
* ckd patients with stage 3,4
* CABG for the first time

Exclusion Criteria

* age\<18
* previous CABG (coronary artery bypass grafting)
* AKI(acute kidney injury)
* dialysis patients
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tehran University of Medical Sciences

OTHER

Sponsor Role collaborator

Imam Khomeini Hospital

OTHER

Sponsor Role lead

Responsible Party

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Mohammad Reza Khatami

Member of research board of Nephrology ResearchCenter of Tehran University of Medical Sciences

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Roghieh Borji, MD

Role: PRINCIPAL_INVESTIGATOR

Imam Khomeini Hospital

Mohammad R Khatami, MD

Role: STUDY_DIRECTOR

Nephrology research Center

Seyyed Hossein Ahmadi, MD

Role: STUDY_CHAIR

Tehran Herat Center

Khosro Barkhordari, MD

Role: PRINCIPAL_INVESTIGATOR

Tehran Heart Center

Mohammad R Abbasi, MD

Role: PRINCIPAL_INVESTIGATOR

Nephrology Researc Center

Locations

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Tehran Herat Center

Tehran, Tehran Province, Iran

Site Status RECRUITING

Countries

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Iran

Central Contacts

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Mohamamd R khatami, MD

Role: CONTACT

00982161192659

Roghieh Borji, MD

Role: CONTACT

009891254590988

Facility Contacts

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M R Khatami, MD

Role: primary

R Borji, MD

Role: backup

Other Identifiers

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THC-473

Identifier Type: -

Identifier Source: org_study_id

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