DNA Methylation and Urothelial Carcinoma

NCT ID: NCT01378052

Last Updated: 2011-06-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-06-30

Brief Summary

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Many studies previously showed the significant association between urinary arsenic profiles and urothelial carcinoma (UC) risk and observed the increased UC risk in people with lower plasma folate and higher homocysteine than those with higher plasma folate and lower homocysteine. The investigators would expect to explore the interactions among global DNA methylation, one-carbon metabolic pathway factors, urinary arsenic profiles and UC.

Detailed Description

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Conditions

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Urothelial Carcinoma

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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urothelial carcinoma pateints

No interventions assigned to this group

healthy controls

Age and gender matched control subjects with no evidence of UC or any other malignancy were accrued from the hospital, recruiting people receiving adult health examinations at China Medical University Hospital.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Clinical diagnosis of urothelial carcinoma
* The voluntary of participating the study

Exclusion Criteria

* Age smaller than 20 years
* Pregnant women
* Not willing to participate the study because of their personal reasons
Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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China Medical University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Department of Urology

Principal Investigators

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Chi-Jung Chung, PhD

Role: PRINCIPAL_INVESTIGATOR

Department of Health risk Management, China Medical University

Locations

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Department of Urology, China Medical University Hospital

Taichung, 404, Taiwan

Site Status RECRUITING

Countries

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Taiwan

Central Contacts

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Chao-Hsiang Chang, PhD

Role: CONTACT

886-4-22052121 ext. 4439

Facility Contacts

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Chao-Hsiang Chuang, PhD

Role: primary

886-4-22052121 ext. 4439

Other Identifiers

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DMR100-IRB-092

Identifier Type: -

Identifier Source: org_study_id

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