Time - Related Cuff Pressure and Volume of the Laryngeal Tube With the Use of Nitrous Oxide

NCT ID: NCT01346384

Last Updated: 2011-05-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

75 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-05-31

Study Completion Date

2009-12-31

Brief Summary

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The purpose of this study is to investigate the time-related intracuff pressure and volume change (which reflects the pharyngeal pressure) of the LT during anesthesia with N2O.

Detailed Description

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Background : The laryngeal tube airway (LT) is an extraglottic airway device with a proximal and distal conical cuff designed to secure a patient's airway during either spontaneous breathing or controlled ventilation. Application of this device with the use of N2O may be related to the ischemic change of the oropharyngeal mucosa. The objective of this study was to investigate the time-related intracuff pressure and volume change (which reflects the pharyngeal pressure) of the LT during anesthesia with N2O.

Methods : Seventy-five patients were studied with the use of LT size 4. N2O (66%) and isoflurane were used to maintain anesthesia. Initial intracuff pressure and volume were recorded for airway sealing during ventilation. Time-course changes of the intracuff pressure followed by recording every 10 min. If the intracuff pressure reached 100 cmH2O, the cuff was deflated to the initial intracuff pressure and the volume of deflated air and postoperative airway complications were recorded.

Conditions

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Adult Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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intracuff pressure N2O

measured intracuff pressure of LT with N2o during operative period

laryngeal tube (VBM Medizintechnik)

Intervention Type DEVICE

laryngeal tube number 4

Interventions

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laryngeal tube (VBM Medizintechnik)

laryngeal tube number 4

Intervention Type DEVICE

Other Intervention Names

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The laryngeal tube (VBM Medizintechnik, Sulz, Germany)

Eligibility Criteria

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Inclusion Criteria

* American Society of Anesthesiologist physical status I or II
* Undergoing elective orthopedic surgery and surgery of breast under general anesthesia with an expected duration of 60 min or more

Exclusion Criteria

* Height was \< 155 or \>180 cm (for the use of laryngeal tube size 4)
* Body mass index ≥35 kg/m2
* Preexisting laryngotracheal disease
* Risk of pulmonary aspiration of gastric contents.
Minimum Eligible Age

15 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Prince of Songkla University

OTHER

Sponsor Role lead

Responsible Party

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Department of Anesthesiology Faculty of Medicine Prince of Songkla University Thailand

Locations

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Songklanagarind Hospital

Hat Yai, Changwat Songkhla, Thailand

Site Status

Countries

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Thailand

Other Identifiers

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LT-N2O

Identifier Type: -

Identifier Source: org_study_id

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