High Sensitive Troponin T (hsTnT) and Copeptin as Prognostic Parameters in Patients With Elective Total Endoprosthesis

NCT ID: NCT01335815

Last Updated: 2011-04-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-03-31

Study Completion Date

2013-03-31

Brief Summary

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Summary: The purpose of the study is to prove if the biomarker high sensitive troponin T (hsTnT) and the biomarker of endogenous stress copeptin can serve as surrogate parameter of prognosis in patients with elective knee and hip total endoprosthesis.

Detailed Description

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Consecutively, high sensitive troponin T and copeptin will be measured in all patients with elective knee and hip endoprosthesis in the orthopedic department of the University of Heidelberg. The blood is taken during the routine blood testes if possible, on admission and the days 1-4 following the operation. Usual baseline characteristics are taken as well as usual blood results (hb, cholesterol and so on). Primary endpoint is the detection of perioperative myocardial infarction and pulmonary embolism.

Conditions

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Perioperative Myocardial Infarctions Pulmonary Embolism

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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elective knee and limb endoprothesis

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Consecutive patients with elective knee and hip endoprosthesis

Exclusion Criteria

* Not willing or not able to take part in the observational trial
* No written inform consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Heidelberg University

OTHER

Sponsor Role lead

Responsible Party

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Department of Cardiology, University of Heidelberg

Principal Investigators

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Evangelos Giannitsis, Prof. Dr.

Role: PRINCIPAL_INVESTIGATOR

Heidelberg University

Locations

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University of Heidelberg

Heidelberg, Baden-Wurttemberg, Germany

Site Status RECRUITING

Countries

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Germany

Central Contacts

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evangelos Giannitsis, Prof. Dr.

Role: CONTACT

0049-6221-56-38686

Facility Contacts

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Evangelos Giannitsis, Prof. Dr.

Role: primary

004962215638686

Other Identifiers

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TnT hs 3

Identifier Type: -

Identifier Source: org_study_id

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