Length of Stay and Complications in High-risk Patients Receiving Fast-track Total Hip (THA) or Knee- Alloplasty (TKA)

NCT ID: NCT01515670

Last Updated: 2021-06-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

60000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-02-28

Study Completion Date

2019-01-31

Brief Summary

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The purpose of the study is to determine the influence of preoperative co-morbidity in relation to increased length of stay and postoperative complications in patients receiving fast-track hip or knee replacement.

Detailed Description

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Preoperative risk assessment is well established and repeatedly demonstrated to be related to adverse postoperative outcomes regarding all organ functions. However, all evidence is based upon conventional care programs and none has been done on fast-track surgery, neither in total hip arthroplasty (THA) or total knee arthroplasty (TKA).

The purpose of this study series is therefore to evaluate the importance of conventional risk factors in an optimised fast-track TKA and THA set-up. These studies will be performed in the Lundbeck Foundation Center for fast-track THA and TKA, based on an established database, but with additional detailed risk information to be included in studies of certain types co-morbidity.

The Lundbeck Foundation Center Database prospectively registers patient characteristics and co-morbidity in all patients receiving hip and knee arthroplasty. This is done using a questionaire and with dedicated staff available to help in case of doubt regarding specific questions. Additional information is collected by scrutinizing the patients medical charts. Completeness of data has been shown to be about 95%.

Conditions

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Arthroplasty Complications Co-morbidity Postoperative Morbidity

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Fast-track THA/TKA

Any patient receiving THA/TKA in the participating wards

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Standardized elective fast-track THA or TKA

Exclusion Criteria

* Elective THA or TKA not in regular fast-track setup
* not a Danish citizen
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hvidovre University Hospital

OTHER

Sponsor Role collaborator

Aarhus University Hospital

OTHER

Sponsor Role collaborator

Vejle Hospital

OTHER

Sponsor Role collaborator

Esbjerg Hospital - University Hospital of Southern Denmark

OTHER

Sponsor Role collaborator

Regional Hospital Holstebro

OTHER

Sponsor Role collaborator

Naestved Hospital

OTHER

Sponsor Role collaborator

Bispebjerg Hospital

OTHER

Sponsor Role collaborator

Central Jutland Regional Hospital

OTHER

Sponsor Role collaborator

Aalborg University Hospital

OTHER

Sponsor Role collaborator

Rigshospitalet, Denmark

OTHER

Sponsor Role lead

Responsible Party

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Christoffer Joergensen

Research-fellow

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Christoffer C Joergensen, MD

Role: PRINCIPAL_INVESTIGATOR

Rigshospitalet, Denmark

Locations

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Himmerland Hospital

Farsø, Judland, Denmark

Site Status

Holstebro Regionalhospital

Holstebro, Judland, Denmark

Site Status

Vejle Hospital

Vejle, Judland, Denmark

Site Status

Hvidovre Hospital

Hvidovre, Region Sjælland, Denmark

Site Status

Bispebjerg University Hospital

Copenhagen, , Denmark

Site Status

Gentofte University Hospital

Gentofte Municipality, , Denmark

Site Status

Næstved Hospital

Næstved, , Denmark

Site Status

Countries

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Denmark

References

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Ortved M, Petersen PB, Jorgensen CC, Kehlet H; Lundbeck Foundation Centre for Fast-track Hip and Knee Replacement Collaborative Group. Postoperative Morbidity and Mortality in Diabetic Patients After Fast-Track Hip and Knee Arthroplasty: A Prospective Follow-up Cohort of 36,762 Procedures. Anesth Analg. 2021 Jul 1;133(1):115-122. doi: 10.1213/ANE.0000000000005248.

Reference Type DERIVED
PMID: 33234944 (View on PubMed)

Jorgensen CC, Gromov K, Petersen PB, Kehlet H; Lundbeck Foundation Centre for Fast-track Hip and Knee Replacement Collaborative Group. Influence of day of surgery and prediction of LOS > 2 days after fast-track hip and knee replacement. Acta Orthop. 2021 Apr;92(2):170-175. doi: 10.1080/17453674.2020.1844946. Epub 2020 Nov 12.

Reference Type DERIVED
PMID: 33176546 (View on PubMed)

Petersen PB, Jorgensen CC, Kehlet H; Lundbeck Foundation Center for Fast-track Hip and Knee Replacement collaborative group. Temporal trends in length of stay and readmissions after fast-track hip and knee arthroplasty. Dan Med J. 2019 Jul;66(7):A5553.

Reference Type DERIVED
PMID: 31256778 (View on PubMed)

Jorgensen CC, Petersen MA, Kehlet H; Lundbeck Foundation Centre for Fast-Track Hip and Knee Replacement Collaborative Group. Preoperative prediction of potentially preventable morbidity after fast-track hip and knee arthroplasty: a detailed descriptive cohort study. BMJ Open. 2016 Jan 12;6(1):e009813. doi: 10.1136/bmjopen-2015-009813.

Reference Type DERIVED
PMID: 26758264 (View on PubMed)

Related Links

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http://www.fthk.dk/

The Lundbeck Center for Fast-track Hip and Knee replacement

Other Identifiers

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RH30-0623

Identifier Type: -

Identifier Source: org_study_id

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