Hi-Fatigue G Bone Cement Retrospective Study

NCT ID: NCT06699134

Last Updated: 2025-12-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

90 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-11-19

Study Completion Date

2026-10-31

Brief Summary

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The objective of this retrospective monocentric study is to collect survivorship and clinical data confirming safety, performance and clinical benefits for the Hi-Fatigue G Bone Cement.

The assessments will include:

* Radiological analysis performed at different time points according to the standard of care of the hospital
* Implant survivorship and safety based on removal of a study device
* Patient reported outcome measures (PROMs)

Primary endpoint:

Assessment of radiolucent lines around the components (tibial, femoral, acetabular) at 5 years (in accordance with the hospital standard of care).

Secondary endpoints:

* Evaluation of implant survivorship and safety by monitoring the frequency and incidence of adverse events. Relation of the events to implant, instrumentation and/or procedure should be specified.
* Evaluation of PROMs
* Obtain information regarding the cementing technique and handling of the cement, if available

Detailed Description

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Conditions

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Total Hip and Knee Arthroplasties

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Patients with TKA

Patients with primary total knee replacement using Hi-Fatigue G Bone Cement and a Zimmer Biomet implant

Total knee arthroplasty

Intervention Type DEVICE

Primary total knee replacement using Hi-Fatigue G Bone Cement and a Zimmer Biomet implant

Patients with THA

Patients with primary total hip replacement using Hi-Fatigue G Bone Cement and a Zimmer Biomet implant

Total Hip arthroplasty

Intervention Type DEVICE

Primary total hip replacement using Hi-Fatigue G Bone Cement and a Zimmer Biomet implant

Interventions

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Total knee arthroplasty

Primary total knee replacement using Hi-Fatigue G Bone Cement and a Zimmer Biomet implant

Intervention Type DEVICE

Total Hip arthroplasty

Primary total hip replacement using Hi-Fatigue G Bone Cement and a Zimmer Biomet implant

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Subject qualified for cemented TKA or THA with a Zimmer Biomet implant
* Subject is willing and able to give written informed consent for retrospective data collection and undergo interim and final evaluation (X-Ray \& Scores completion)
* Subject \> 18 years old

Exclusion Criteria

* Muscle wasting
* Neuromuscular compromise in the affected limb
* Known hypersensitivity to any of the cement constituents
* Subjects with severe renal failure
* Bilateral interventions
* Subject is a vulnerable subject (prisoner, mentally incompetent or unable to understand what participation to the study entails, known alcohol or drug abuser, anticipated to be non-compliant)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Zimmer Biomet

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Klinikum Weiden

Weiden, Bavaria, Germany

Site Status RECRUITING

Countries

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Germany

Central Contacts

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Miguel Correa-Tapia

Role: CONTACT

+41791522905

Linda Meijer

Role: CONTACT

+31657933741

Facility Contacts

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Christian von Rüden

Role: primary

00490961 303-0

Other Identifiers

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CME2020-38C

Identifier Type: -

Identifier Source: org_study_id

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