Endometrial Biopsy Protocol for In Vitro Fertilization (IVF)

NCT ID: NCT01278706

Last Updated: 2011-01-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-01-31

Brief Summary

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Endometrial biopsy has been shown to improve IVF pregnancy and live birth rates. The optimal time of performing the biopsy is yet to be established.

In this study, the investigators will compare different temporal timing of the biopsies with regards to the menstrual cycle and their affect on the success rates of the treatment.

Detailed Description

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Conditions

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Infertility Recurrent Implantation Failure

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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no treatment

Group Type NO_INTERVENTION

No interventions assigned to this group

one biopsy, proliferative phase

Group Type EXPERIMENTAL

endometrial biopsy/ies

Intervention Type PROCEDURE

performing office endometrial biopsy with a disposable sterile catheter

one biopsy, secretory phase

Group Type EXPERIMENTAL

endometrial biopsy/ies

Intervention Type PROCEDURE

performing office endometrial biopsy with a disposable sterile catheter

two biopsies

Group Type EXPERIMENTAL

endometrial biopsy/ies

Intervention Type PROCEDURE

performing office endometrial biopsy with a disposable sterile catheter

Interventions

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endometrial biopsy/ies

performing office endometrial biopsy with a disposable sterile catheter

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* normal menstrual cycle
* between 1-6 previous failed IVF cycles
* normal hormonal profile

Exclusion Criteria

* intrauterine procedure in last 3 months
* hydrosalpinx
* intrauterine lesion /malformation
Minimum Eligible Age

18 Years

Maximum Eligible Age

38 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Kaplan Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Kaplan Medical Center

Locations

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Kaplan Medical Center, IVF Unit

Rehovot, , Israel

Site Status

Weizmann Institute of Science

Rehovot, , Israel

Site Status

Countries

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Israel

Central Contacts

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Dan Levin, M.D.

Role: CONTACT

+972-89441623

Irit Granot, Ph.D.

Role: CONTACT

+972-8-9441623

Facility Contacts

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Levin

Role: primary

+972-8-9441623

Other Identifiers

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kmc110154CTIL

Identifier Type: -

Identifier Source: org_study_id

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