Cosmesis and Body Image After Single Port or 4-Port Laparoscopic Cholecystectomy

NCT ID: NCT01278472

Last Updated: 2011-01-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

110 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-01-31

Study Completion Date

2012-12-31

Brief Summary

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Laparoscopic Cholecystectomy (LC) is the treatment of choice for symptomatic gallstone disease. Single-port access cholecystectomy (SL) has been recently introduced using only one, trans-umbilical placed port. The method has been denominated as ''scarless.'' However, it is unknown whether SL significantly improves body and cosmesis images as well as the quality of life (QoL), reported directly by the patients. Furthermore SL promises to reduce postoperative pain and to be cost-effective due a faster postoperative recovery.

The aim of this Double Blind Randomized Controlled Trial (RCT) is to demonstrate whether SL is superior to LC in improving patients', body and cosmesis images as well as QoL and to analyse cost-efficiency.

Based on the sample size calculations, a total of 110 patients will be randomised to either LC or SL. The primary endpoint will be the cosmetic score. Costs, pain, time to convalescence, quality of life and complications and will also be compared as secondary endpoints.

This study will provide evidence-based patient-oriented information regarding the SL procedure and its further use.

Detailed Description

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Conditions

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Symptomatic Gallstone Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Single Port Cholecystectomy

Laparoscopic Cholecystectomy with single port transumbilical access

Group Type EXPERIMENTAL

Single Port Cholecystectomy

Intervention Type DEVICE

Using transumbilical single port device: SILS Port

4 Port Cholecystectomy

Laparoscopic Cholecystectomy using 4 separate conventional trocars

Group Type ACTIVE_COMPARATOR

4 Port Cholecystectomy

Intervention Type DEVICE

using 4 separate skin incisions and 2 5mm and 2 12 mm conventional ports

Interventions

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Single Port Cholecystectomy

Using transumbilical single port device: SILS Port

Intervention Type DEVICE

4 Port Cholecystectomy

using 4 separate skin incisions and 2 5mm and 2 12 mm conventional ports

Intervention Type DEVICE

Other Intervention Names

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SILS PT5, Covidien Inc.

Eligibility Criteria

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Inclusion Criteria

1. Patients above 18 years of age for elective cholecystectomy
2. Written informed consent from the subject
3. INR \< 1.4, platelet count \> 50'000/mcl

Exclusion Criteria

1. Women in pregnancy
2. Contraindications on ethical grounds
3. Severe coagulopathy (platelet \< 50'000/mcl, double medication on platelet antagonists (Plavix and Aspirin), INR \> 1.4
4. liver cirrhosis
5. Enrolment of the investigator, his/her family members, employees and other dependent persons
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Zurich

OTHER

Sponsor Role lead

Responsible Party

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University Hospital Zurich, Division of Visceral and Transplantation Surgery

Principal Investigators

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Stefan Breitenstein, PD, MD

Role: PRINCIPAL_INVESTIGATOR

University of Zurich

Locations

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University Hospital Zurich, Division of Visceral and Transplantation Surgery

Zurich, Canton of Zurich, Switzerland

Site Status RECRUITING

Countries

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Switzerland

Central Contacts

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Stefan Breitenstein, PD, MD

Role: CONTACT

044 255 33 00

Daniel C Steinemann, MD

Role: CONTACT

044 255 92 84

Facility Contacts

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Daniel C Steinemann, MD

Role: primary

044 255 92 84

References

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Lurje G, Raptis DA, Steinemann DC, Amygdalos I, Kambakamba P, Petrowsky H, Lesurtel M, Zehnder A, Wyss R, Clavien PA, Breitenstein S. Cosmesis and Body Image in Patients Undergoing Single-port Versus Conventional Laparoscopic Cholecystectomy: A Multicenter Double-blinded Randomized Controlled Trial (SPOCC-trial). Ann Surg. 2015 Nov;262(5):728-34; discussion 734-5. doi: 10.1097/SLA.0000000000001474.

Reference Type DERIVED
PMID: 26583659 (View on PubMed)

Steinemann DC, Raptis DA, Lurje G, Oberkofler CE, Wyss R, Zehnder A, Lesurtel M, Vonlanthen R, Clavien PA, Breitenstein S. Cosmesis and body image after single-port laparoscopic or conventional laparoscopic cholecystectomy: a multicenter double blinded randomised controlled trial (SPOCC-trial). BMC Surg. 2011 Sep 12;11:24. doi: 10.1186/1471-2482-11-24.

Reference Type DERIVED
PMID: 21910897 (View on PubMed)

Other Identifiers

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2010-0321/4

Identifier Type: -

Identifier Source: org_study_id

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