Creatine Supplementation and Cognition

NCT ID: NCT01164020

Last Updated: 2013-01-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

56 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-08-31

Study Completion Date

2012-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Resistance training as well as creatine supplementation may be beneficial for cognitive function, such as memory and attention. Therefore, the investigators speculate that resistance training combined with creatine supplementation would promote additive benefits on cognitive function in elderly women.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Cognition Aging

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

placebo control

this only receives placebo (dextrose)

Group Type PLACEBO_COMPARATOR

Placebo (Dextrose)

Intervention Type OTHER

20g/d for 7 days followed by 5g/d for 23 weeks

placebo and exercise

this is trained and receives placebo

Group Type EXPERIMENTAL

Placebo (Dextrose)

Intervention Type OTHER

20g/d for 7 days followed by 5g/d for 23 weeks

Resistance training

Intervention Type OTHER

resistance training twice a week for 24 weeks

creatine supplementation

this is non-exercise trained and receives creatine supplementation

Group Type EXPERIMENTAL

creatine supplementation

Intervention Type DIETARY_SUPPLEMENT

20g/d for 7 days followed by 5g/d for 23 weeks

Creatine and Exercise

this is exercised trained and receives creatine supplementation

Group Type EXPERIMENTAL

creatine supplementation

Intervention Type DIETARY_SUPPLEMENT

20g/d for 7 days followed by 5g/d for 23 weeks

Resistance training

Intervention Type OTHER

resistance training twice a week for 24 weeks

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

creatine supplementation

20g/d for 7 days followed by 5g/d for 23 weeks

Intervention Type DIETARY_SUPPLEMENT

Placebo (Dextrose)

20g/d for 7 days followed by 5g/d for 23 weeks

Intervention Type OTHER

Resistance training

resistance training twice a week for 24 weeks

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* women older than 60 years old

Exclusion Criteria

* cardiovascular diseases or muscular disturbances precluding exercise training
* drugs affecting the cognition
Minimum Eligible Age

60 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

University of Sao Paulo

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Bruno Gualano

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Bruno Gualano, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Sao Paulo

Antonio H Lancha Junior, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Sao Paulo

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

School of Medicine - Division of Rheumatology

São Paulo, São Paulo, Brazil

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Brazil

References

Explore related publications, articles, or registry entries linked to this study.

Alves CR, Merege Filho CA, Benatti FB, Brucki S, Pereira RM, de Sa Pinto AL, Lima FR, Roschel H, Gualano B. Creatine supplementation associated or not with strength training upon emotional and cognitive measures in older women: a randomized double-blind study. PLoS One. 2013 Oct 3;8(10):e76301. doi: 10.1371/journal.pone.0076301. eCollection 2013.

Reference Type DERIVED
PMID: 24098469 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

Creatine and Cognition

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Creatine Supplementation in Chronic Fatigue Syndrome
NCT02374112 ACTIVE_NOT_RECRUITING NA
Beta-alanine and Elder Endurance
NCT02821481 COMPLETED NA