Genomics of Primary Sclerosing Cholangitis (PSC)

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2002-03-31

Study Completion Date

2025-07-31

Brief Summary

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Primary Sclerosing Cholangitis (PSC) is a progressive liver disorder of unknown cause. Current evidence suggests that genes, the genetic material we inherit from our parents, in combination with environmental factors, likely play an important role in the development of PSC.

This study is being done to investigate whether genes make people more likely to develop PSC. Discovery of these genes will help us to better understand how PSC developes and subsequently, to apply new approaches for its prevention, diagnosis and treatment.

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Detailed Description

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Conditions

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Primary Sclerosing Cholangitis (PSC)

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Interventions

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Genetic Analysis

Perform Genome Wide Association Studies.

Intervention Type GENETIC

Eligibility Criteria

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Inclusion Criteria

* Men, Women, and Children between the ages of 5-90 with a history of PSC.
* PSC patients who have had a liver transplant are eligible.
* Family members (1st degree relatives) of enrolled PSC patients are eligible.